中国寄生虫学与寄生虫病杂志 ›› 2017, Vol. 35 ›› Issue (3): 246-249.

• 论著 • 上一篇    下一篇

新疆维吾尔自治区北部地区6~12岁儿童棘球蚴病血清学调查

买买提江·吾买尔1,2, 阿斯亚·阿西木1, 王端明1, 伊斯拉音·乌斯曼1, 肖宁2,*()   

  1. 1 新疆维吾尔自治区疾病预防控制中心,乌鲁木齐 830002
    2 中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织热带病合作中心,科技部国家级热带病国际联合中心,卫生部寄生虫病原与媒介生物学重点实验室,上海 200025
  • 收稿日期:2017-01-19 出版日期:2017-03-30 发布日期:2017-09-07
  • 通讯作者: 肖宁

Serological survey on hydatid disease in children of 6-12 years in the northern region of Xinjiang Uygur Autonomous Region

WUMAIER Maimaitijiang1, ASIMU Asiya1, Duan-ming WANG1, OSMAN Yisilayin1, Ning XIAO2,*()   

  1. 1 The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region, Urumuqi 830002, China
    2 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China
  • Received:2017-01-19 Online:2017-03-30 Published:2017-09-07
  • Contact: Ning XIAO

摘要: 目的 了解新疆维吾尔自治区(简称新疆)北部地区(北疆)6~12岁儿童棘球蚴病流行现状。 方法 2012年8月-2013年9月,对北疆伊犁哈萨克自治州、博尔塔拉蒙古自治州、塔城地区、阿勒泰地区、克拉玛依市、昌吉回族自治州、乌鲁木齐市、吐鲁番地区和哈密地区等9个地区(州、市)采用分层抽样的方法抽取200所小学,对6~12岁儿童采集血样,用棘球蚴IgG抗体检测试剂盒ELISA检测儿童血清抗体水平。血清抗体阳性率间的比较采用χ2检验。 结果 共检测6~12岁儿童89 006人,血清抗体阳性者1 956例,阳性率为2.20%,其中塔城地区最高,为3.91%(510/13 027);吐鲁番地区最低,为0.56%(32/5 765)(χ2 = 161.06,P < 0.05)。男性儿童阳性率为3.12%(998/47 006),女性为2.23%(958/42 000)。12岁组阳性率最高,为2.38%(505/21 178);10岁组最低,为2.10%(306/14 594)(χ2 = 3.23,P > 0.05),6~12岁各年龄组间差异无统计学意义(χ2 = 0~3.23,P > 0.05)。在调查儿童中,哈萨克族、蒙古族、回族、汉族、维吾尔族儿童占调查总数的99.23%(88 497/89 006),阳性率分别为3.09%(971/31 417)、2.81%(33/1 176)、1.82 %(174/9 564)、1.70%(559/32 965)和1.58%(211/13 373),哈萨克族和蒙古族儿童阳性率高于回族、汉族和维吾尔族(χ2 = 5.37~9.89,P < 0.05)。 结论 北疆6~12岁儿童棘球蚴病血清抗体阳性率仍处于一个相对较高的水平,尤其是放牧为主的哈萨克族和蒙古族儿童.

关键词: 棘球蚴病, 血清学调查, 儿童, 北疆

Abstract: Objective To understand the epidemiological situation of hydatid disease in children aged 6-12 years in the northern region of Xinjiang Uygur Autonomous Region. Methods Children aged 6 to 12 years in 200 primary schools selected by stratified sampling were made in 9 regions/states/municipalities (Ili Kazak Autonomous Prefecture, Bortala Mongolia Autonomous Prefecture, Tacheng, Altay, Karamay, Changji Hui Autonomous Prefecture, Urumqi, Turpan and Hami) in northern Xinjiang from August 2012 to September 2013. The serum level of anti-echinococcus IgG were determined by ELISA. Data were analyzed with χ2 test. Results A total of 89 006 children were examined, and 1 956(2.20%) were positive for anti-echinococcus IgG. Among the sites of survey, the positive rate was highest in Tacheng (3.91%, 510/13 027), and lowest in Turpan (0.56%, 32/5 765) (χ2 = 161.06, P < 0.05). The positive rate in males was 3.12% (998/47 006) and that in females was 2.23% (958/42 000). Among different age groups, the positive rate was highest in the group of 12 years (2.38%, 505/21 178) and lowest in 10 year group (2.10%, 306/14 594) (χ2 = 3.23, P > 0.05). There was no significant difference among the age groups (χ2 = 0-3.23, P > 0.05). Children of Kazakh, Mongolian, Hui, Han, and Uygur nationalities accounted for 99.23% (88 497/89 006), with a positive rate of 3.09% (971/31 417), 2.81% (33/1 176), 1.82% (174/9 564), 1.70% (559/32 965) and 1.58% (211/13 373), respectively. The positive rates in children of Kazak and Mongolian ethnicities were significantly higher than those of Hui, Han and Uygur ethnicities (χ2 = 5.37-9.89, P < 0.05). Conclusions There remains a relatively high sera-prevalence of echinococcosis in children of 6 to 12 years in the northern region of Xinjiang, especially in those of Kazak and Mongolian nationalities.

Key words: Echinococcosis, Serosurvey, Children, Northern region of Xinjiang

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