关键词: 丝虫病, 病原学, 蚊媒, IFAT, 监测, 消灭

Abstract: AIM: To observe the long term effect and the dynamics of prevalence of filariasis after the disease has been basically eradicated and to provide scientific evidence for the eradication of filariasis. METHORD: Microfilaremia and the antibody level were detected by IFAT. The vector mosquitoes were dissected for the filarial larvae. RESULTS: The microfilaria rate was further reduced from 0.021% in the first year after filariasis was basically eradicated to 0.001% in the ninth year. No microfilaremia case was found in the following decade. The surveillance covering rates of the population of the township, village and endemic area were 71.0%, 29.9% and 14.6%, respectively in the first ten years, whereas in the following ten years the covering rates were 37.0%, 8.5% and 3.8% and no microfilaremia case could be detected. No natural infection of filarial larvae in Culex pipiens quinquefasciatus (n= 711 823), Anopheles anthropophagus and A. sinensis (n=13 007) was found as a whole. The annual average positive rate of filarial antibodies in inhabitants(n=259 934) living in endemic area detected by IFAT ranged from 1.69% to 3.90%. There was no significant difference between the filarial antibody levels of inhabitants both living in endemic area and in non endemic area. CONCLUSION: It is suggested that the transmission of filariasis in Guangxi has been interrupted and filariasis has been eradicated.