关键词: 棘球蚴病, 分子致病机制, 疫苗研制, 手术治疗, 药物治疗

Abstract:

 Echinococcosis is an important communicable disease that has remarkable impacts on the global health. The disease is highly endemic in western China. In the last decades, achievements were obtained for the surgery and drug therapies for echinococcosis, as well as for studies on genomics, signaling pathways, and liver proliferation and injury of the intermediate hosts. Although steps have entered vaccine development, challenges remain in immunodiagnosis and drug treatment for intermediate hosts, and in vaccine development for definitive hosts. This paper gives an overview on the current achievements and challenges for echinococcosis control.

Key words: Echinococcosis, Molecular mechanism, Vaccine development, Surgery, Drug therapy