中国寄生虫学与寄生虫病杂志 ›› 2020, Vol. 38 ›› Issue (5): 647-652.doi: 10.12140/j.issn.1000-7423.2020.05.019

• 综述 • 上一篇    下一篇

蚊虫嗅觉受体研究进展

王洋1,2(), 李婷婷3, 公茂庆1,*()   

  1. 1 山东省寄生虫病防治研究所,山东第一医科大学(山东省医学科学院),济宁 272033
    2 济南大学,山东省医学科学院医学与生命科学学院,济南 250062
    3 济宁医学院第二临床医学院,济宁 272067
  • 收稿日期:2020-01-20 出版日期:2020-10-30 发布日期:2020-11-12
  • 通讯作者: 公茂庆
  • 作者简介:王洋(1995-),男,硕士研究生,从事媒介昆虫抗药性治理及抗性分子机制研究。E-mail:wyyang1221@163.com
  • 基金资助:
    国家自然科学基金(81672059);国家自然科学基金(81871685);山东省重点研发计划项目(2019GSF111006)

Advances in research on olfactory receptors of mosquitoes

WANG Yang1,2(), LI Ting-ting3, GONG Mao-qing1,*()   

  1. 1 Shandong Institute of Parasitic Diseases, Shandong First Medical University, Shandong Academy of Medical Sciences, Jining, 272033, China
    2 School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250062, China
    3 The Second School of Clinical Medicine, Jining Medical University, Jining 272067, China
  • Received:2020-01-20 Online:2020-10-30 Published:2020-11-12
  • Contact: GONG Mao-qing
  • Supported by:
    National Natural Science Foundation of China(81672059);National Natural Science Foundation of China(81871685);Shandong Province Key Research and Development Project(2019GSF111006)

摘要:

蚊虫的许多行为都依赖于嗅觉系统,如通过宿主或自然环境释放的气味,进行摄食、求偶、寻找宿主和吸血,因此蚊虫嗅觉系统对其适应外界环境和种群的繁衍有着极其重要的意义。嗅觉受体(ORs)作为传递气味信息的枢纽,在蚊虫嗅觉行为中起着关键作用。因此,在了解蚊虫嗅觉行为的基础上,阐明蚊虫ORs的基因表达特征、由其介导的嗅觉信号转导机制及其与驱避剂的关系,有助于提高我们对蚊虫嗅觉的认识,为基于蚊虫嗅觉的新防控措施提供科学依据。

关键词: 蚊虫, 嗅觉受体, 驱避剂

Abstract:

Many behaviors of mosquitoes rely on the olfactory system, such as feeding, mating, seeking host and blood-sucking through odors released by the host or natural environment. Therefore, the olfactory system is crucial for mosquitoes in adaptation of to the external environment and population reproduction. Mosquito olfactory receptors(ORs), which serve as a hub for transmitting odor information, play a key role in odor-evoked behaviors. Therefore, based on understanding of mosquito odor-evoked behaviors, to elucidate the characteristics of OR gene expression, and the mechanisms of OR-mediated olfactory signal transductionin association with the design of repellents, can further advance the knowledge of mosquito olfaction, thereby providing scientific basis for development of new measures for mosquito control.

Key words: Mosquito, Olfactory receptors, Repellents

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