人皮肤微生物对蚊虫嗅觉行为影响的研究进展

doi:10.12140/j.issn.1000-7423.2022.01.014

摘要/Abstract

摘要：

蚊虫是疟疾、登革热、黄热病等传染病的传播媒介。蚊虫防制可以降低传染病的发生和流行。近年来研究发现,人皮肤微生物的代谢产物或产生的挥发性气味物质对蚊虫具有一定的吸引力,有望为蚊虫控制提供新方法。本文就人皮肤微生物的组成、分布及其产生的挥发性气味物质对蚊虫嗅觉行为的影响进行综述,为新型蚊虫驱避剂和引诱剂的开发及应用提供参考。

关键词: 蚊虫, 嗅觉行为, 人皮肤微生物, 挥发性物质, 引诱

Abstract:

Mosquitoes are the vectors for many infectious diseases, including malaria, dengue and yellow fever. Mosquito control measures can reduce the transmission of these infectious diseases. In recent years, it has been discovered that the metabolites or volatile odorants produced by human skin microbiota are attractive to mosquitoes, which is expected to provide new methods for mosquito control approaches. In this review, we summarized the composition and distribution of human skin microbiota and the effects of volatile odorants on the mosquito olfactory behavior, which may provide a foundation for the development and implementation of novel mosquito repellents and attractants.

Key words: Mosquitoes, Mosquito’s olfactory behavior, Human skin microbiota, Volatile organic chemical, Attraction

中图分类号:

R384.11

郭红霞, 赵腾, 吴家红, 李春晓. 人皮肤微生物对蚊虫嗅觉行为影响的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(1): 94-98.

GUO Hong-xia, ZHAO Teng, WU Jia-hong, LI Chun-xiao. Research progress on the effects of human skin microbiota on mosquito olfactory behavior[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2022, 40(1): 94-98.

图/表 2

表1

表2

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身体部位	细菌类型	参考文献
足部	葡萄球菌、棒状杆菌、表皮短杆菌、微球菌、铜绿假单胞菌、康秕孢子菌、丙酸杆菌、放线菌、乳杆菌、链球菌、肠杆菌、奈瑟菌、巴氏杆菌、变形杆菌	[22, 25-27]
肘部	铜绿假单胞菌	[28]
上背部	丙酸杆菌、葡萄球菌	[29]
脸颊和掌前臂	变形杆菌、拟杆菌	[29]
手部	丙酸杆菌、葡萄球菌、棒状杆菌、链球菌	[30]
腋窝	棒状杆菌、葡萄球菌、β变形杆菌、乳杆菌、丙酸杆菌、链球菌	[31]

细菌	常见的挥发性化合物	参考文献
葡萄球菌	异戊酸、丁酸、吲哚、异丁酸、3-甲基吲哚、2-甲基丁醛^a、2-甲基丁酸^a、3-甲基丁醛^a、3-甲基丁酸^a、3-甲基-1-丁醇^a、丁酸丁酯、2-甲基丁酸丁酯、乙酸丁酯	[14, 25-26, 41-42]
丙酸杆菌	2-甲基丁酸^a、3-甲基丁酸^a	[26]
棒状杆菌	3-甲基-2-己烯酸、3-羟基-3-甲基-己烯酸、硫醇、2-甲基丁酸^a、乙酸丁酯、3-甲基丁酸^a、丁酸丁酯、2-甲基丁酸丁酯	[21, 26, 29, 42]
枯草芽孢杆菌	乙酸丁酯、丁酸丁酯、二甲基二硫醚、 2-甲基丁酸丁酯	[29]
表皮短杆菌	乙酸丁酯、丁酸丁酯、2-甲基丁酸丁酯	[29]