毛囊蠕形螨感染与头面部皮肤肿瘤的关系

中国寄生虫学与寄生虫病杂志 ›› 2005, Vol. 23 ›› Issue (6): 11-431.

毛囊蠕形螨感染与头面部皮肤肿瘤的关系

孙静*,桂贤,何金,刘会敏,余宏宇,夏春燕,徐毅

第二军医大学长征医院病理科, 上海 200003

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2005-12-30 发布日期:2005-12-30

The Relationship between Infestation of Demodex folliculorumand Epidermal Neoplasm on Face

SUN Jing*,GUI Xian,HE Jin,LIU Hui-min,YU Hong-Yu,XIA Chun-yan,XU Yi,

Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China

Received:1900-01-01 Revised:1900-01-01 Online:2005-12-30 Published:2005-12-30

摘要/Abstract

摘要： 目的探讨毛囊蠕形螨感染与面部表皮肿瘤的关系。方法回顾性收集近4年头面部皮肤基底细胞癌、鳞状细胞癌、皮脂溢出性角化病和外毛根鞘瘤病理存档资料共153例，分析153例4种肿瘤中毛囊蠕形螨的感染率，以及与部位和年龄的关系。结果 153例4种肿瘤中毛囊蠕形螨的感染率存在差异（P<0.05），基底细胞癌、皮脂溢出性角化病、外毛根鞘瘤和鳞状细胞癌患者的蠕形螨感染率分别为56%（20/36）、21%（3/20）、20%（3/15）和14%（17/81），基底细胞癌的蠕形螨感染率明显高于其他3种肿瘤的（P<0.05）。头面部各部位肿瘤的蠕形螨感染率也有不同，发生在鼻部肿瘤的毛囊蠕形螨感染率为71%，明显高于其他部位（P<0.05）。另外，鼻部肿瘤毛囊蠕形螨感染阳性的12例中，有9例是基底细胞癌。而36例基底细胞癌中有10例发生在鼻部。结论在4种肿瘤中以基底细胞癌的蠕形螨感染率最高，面部各部位的肿瘤中以鼻部肿瘤的毛囊蠕形螨感染率最高。

关键词: 毛囊蠕形螨, 组织病理学, 表皮肿瘤

Abstract: Objective To discuss the relationship between infestation of Demodex folliculorum and facial epidermal neoplasm. Methods A retrospective analysis was made with the pathological data of 153 cases collected in the recent four years on facial basal cell carcinoma, squamous cell carcinoma, seborrheic keratosis and trichilemmoma. The infection rate of Demodex folliculorum in the four types of neoplasm was evaluated and the relationship between the infection rate and the location of neoplasm and age was analyzed by V2 test. Results There was a significant difference in the infestation rate of Demodex folliculorum in the four types of epidermal neoplasm(P<0.05), with the highest rate in basal cell carcinoma（56%）, compared with seborrheic keratosis(21%), trichilemmoma(20%), and squamous cell carcinoma(14%). The infestation rate of Demodex folliculorum was significantly different in variant locations of epidermal neoplasm (P<0.05). The highest infestation rate was in cases of nasal neoplasm(71%), compared with other parts. In addition, among twelve cases of Demodex folliculorum positive nasal neoplasm, nine were basal cell carcinoma；ten of thirty-six basal cell carcinoma occurred on nose. Conclusion The highest infestation rate of Demodex folliculorum was in cases of nasal epidermal neoplasm compared with other locations, and the cases of basal cell carcinoma showed the highest infestation rate among the four types of neoplasm.

Key words: Demodex folliculorum, Histopathology, Epidermal neoplasm

孙静;桂贤;何金;刘会敏;余宏宇;夏春燕;徐毅. 毛囊蠕形螨感染与头面部皮肤肿瘤的关系[J]. 中国寄生虫学与寄生虫病杂志, 2005, 23(6): 11-431.

SUNJing*;GUIXian;HEJin;LIUHui-min;YUHong-Yu;XIAChun-yan;XUYi;. The Relationship between Infestation of Demodex folliculorumand Epidermal Neoplasm on Face[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2005, 23(6): 11-431.

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