关键词: 肝纤维化, 肝炎后肝硬化, 血吸虫病性, 慢性活动性肝炎, 鉴别诊断指标, 地衣红, 血吸虫卵, 显著性差异, 乙型肝炎, 浙江衢州

Abstract: The incidence of advanced schistosomiasis complicated with chronic viral hepatitis was found as high as 72.1% by biopsis, immunological and biochemical examinations in 68 cases of hepatic discases. The histologie changes in the post-hepatitic cirrhosis are: degeneration or necrosis of the liver cells, formation and/or swelling of bile ductule, and infiltration by lymphocytes. Among these cases, positive result of Orcein staining may indicate HBV infcction, while negative result of HBsAg associated with positive result of anti-HBc-IgM probably show a new infection of HBV. Both HBsAg and anti- HBc-IgM positive or associated with HBeAg positive may indicate the multiplication of viruses. The differential points between schistosomal fibrosis and post-hepatic cirrhosis are as follows: The oval tubercles and the infiltration of collagenous fibers are found in the hepatic lobules and the portal areas. The pseudolobules causcd by the fibrotic septum have not been formed. On the other hand, the infiltration of the inflammatory cells is not obvious. Serum RF, ANA and AFP examinations are hclpful in diffcrentia-ting chronic active hepatitis. CIC and MAO assaies have definite significance for progno-sis and diagnosis. In addition, dynamic changes in liver. functions and serum lipid, HDL-C/T. Ch0.3, tend to indicate the post-hepatic cirrhosis.