中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (4): 288-290.

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药物治疗小鼠体内钩虫移行期幼虫的效果

杨超,张孝蓉,廖祖瑜   

  1. 四川省医学科学院寄生虫病防治研究所
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1987-11-30 发布日期:2017-01-12

ANTHELMINTICS AGAINST MIGRATING STAGE LARVAE OF ANCYLOSTOMA DVODENALE IN MICE

  • Received:2017-01-12 Revised:2017-01-12 Online:1987-11-30 Published:2017-01-12

摘要: 本文报告左旋米唑、阿苯达唑、吡喹酮、甲苯达唑和阿米登太治疗小鼠体内十二指肠钩虫移行期幼虫的疗效。左旋米唑每天34m/kg×3d和阿苯达唑每天181.4mg/kg×5d,治疗钩虫移行期幼虫,其幼虫减少率分别为97.3和97.5%。本研究结果为钩虫病流行区治疗钩虫移行期幼虫。提供了科学依据。

关键词: 移行期, 药物治疗, 十二指肠钩虫, 幼虫感染, 钩虫幼虫, 小鼠, 阿苯达哩, 阿苯达唑, 防治研究, 寄生虫病

Abstract: Mice infected in our laboratory with Ancylostoma duodenale were used to evaluate the effect of levamisole, albendazole, pyquiton, mebendazole and amidantel against the migrating stage larvae. The results showed that levamisole 34 mg/kg·d×3 and albendazole 181.4mg/kg·d×5 exerted promising effect and the reduction rates of larvae were as high as 97.3% and 97.5% respectively.It is recommended that levamisole and albendazole could be used in field trials to control both adults and migrating larvae of A. duodenale.