中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (3): 220-223.

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日本血吸虫病与肝癌关系的病例——对照研究

郭志荣,陆启新   

  1. 苏州市血吸虫病防治站; 苏州市血吸虫病防治办公室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1987-08-31 发布日期:2017-01-12

A CASE-CONTROL STUDY ON THE RELATIONSHIP BETWEEN SCHISTOSOMIASIS JAPONICA AND LIVER CANCER

  • Received:2017-01-12 Revised:2017-01-12 Online:1987-08-31 Published:2017-01-12

摘要: 本文进行了日本血吸虫病与肝癌关系的病例-对照研究。病例为昆山县1982~1983年间具有Ⅰ级和Ⅱ级诊断依据的肝癌死亡者,对照为同期死于非消化道恶性肿瘤病例和健康人,病例和对照按性别、年龄等1:2配对,共166对。病例组与对照组的日本血吸虫病史有显著差异;确诊血吸虫病年限与相对危险度之间有显著的剂量反应关系;调整了吸烟习惯和肝癌家族史这两个因素后,日本血吸虫病史与肝癌仍有联系.

关键词: 日本血吸虫病, 晚期血吸虫病, 病例-对照研究, 肝癌家族史, 健康人, 病例对照研究, 昆山县, 血吸虫病防治, 消化道恶性肿瘤, 吸烟习惯

Abstract: A case-control study on the relationship between scnistosomiasis japonica and liver cancer was conducted. 166 cases died of liver cancer diagnosed by Ⅰand Ⅱ during 1982 to 1983 were selected and matched pairs by age and sex residence of 1:2 with the same died number of cases of nondigestive tract cancer and 166 healthy people as well. There is a significant difference in schistosomiasis japonica between the two groups. A significant dose-response relativeship between cigarette smoking and relative risk is found. By eliminating the possible factors including smoking habit and family history of liver cancer, there exists a significant difference between schistosomiasis japonica and the occurrence of liver cancer.