关键词: 利什曼原虫, 皮肤利什曼病, 组织学观察, BALB/c小鼠, 吞噬细胞, 墨西哥, 中性粒细胞, 病灶内, 寄生虫病研究所, 纤维母细胞

Abstract: Four BALB/c mice and two CFW mice were inoculated subcutaneously with proma-stigotes of Leishmania gerbilli 3.0 ×106/mouse and Leishmania mexicana amazonensis 3.2 × 106/mouse, respectively.1.5 and 5 months after inoculation, the mice were killed for histopathological examination. Leishmania gerbilli in BALB/c mice was confined mainly to the center of phagocytes. On the contrary, Leishmania mexicana amazonensis in CFW mice was chiefly distributed on the edge of phagocytes.Nearly all the cutaneous tissue of the inoculated mice showed congestion, edema and inflammatory cell infiltration, but the average number of neutrophils and fibroblasts in the foci of BALB/c mice was greater than that in the CFW mice, while the average number of lymphocytes in the foci of CFW mice was greater than that in the BALB/c mice (Table 1 and Plates 1-4).