中国寄生虫学与寄生虫病杂志 ›› 1986, Vol. 4 ›› Issue (2): 126-128.

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对食蟹猴疟原虫复发率的进一步探讨

王兴相,钟玉仙,邓保忠   

  1. 第三军医大学寄生虫学教研室; 昆明军区军事医学研究所; 第三军医大学寄生虫学教研室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1986-05-31 发布日期:2017-01-12

FURTHER STUDIES ON THE RELAPSE OF PLASMODIUM CYNOMOLGI IN RHESUS MONKEYS

  • Received:2017-01-12 Revised:2017-01-12 Online:1986-05-31 Published:2017-01-12

摘要: 用重感染食蟹猴疟原虫的大劣按蚊叮刺感染10只健康恒河猴,每只猴各受到98~169只腺阳性蚊的叮刺.原虫血症前期均为7~8天.6个月内复发率为70%.复发频率最高者四次,最少者一次。对少数不复发的可能原因进行了讨论.

关键词: 食蟹猴疟原虫, 复发率, 恒河猴, 原虫血症, 感染率, 叮刺, 感染后, 寄生虫学, 复发次数, 天然杀伤细胞

Abstract: 10 rhesus monkeys which had been exposed each to the bite of 98-169 Anopheles dims with heavy gland infection of P. cynomolgi were observed for the incidence and frequency of relapses within 6 months after infection.The prepatent periods were 7 or 8 days. Whenever parasitemia was overt, a dose of 20mg/kg of chloroquine base was given orally per day for 3 days. 7 out of 10 monkeys suffered 1-4 relapses. The incidence was similar to that (62.5%) obtained by inoculating isolated sporozoites (0.28-6.5 million) of the same species into rhesus monkeys as reported in our previous paper.