中国寄生虫学与寄生虫病杂志 ›› 1986, Vol. 4 ›› Issue (2): 118-119.

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吡喹酮对体外猪囊尾蚴作用的电镜观察

赵森林,付治锋,李云生,许炽标,尤金英,赵冠宏   

  1. 北京市临床医学研究所电镜室; 北京市临床医学研究所电镜室; 北京市临床医学研究所电镜室; 北京热带医学研究所; 北京热带医学研究所; 北京热带医学研究所
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1986-05-31 发布日期:2017-01-12

ELECTRON MICROSCOPIC OBSERVATION ON CYSTICERCUS CELLULOSAE TREATED WITH PYQUITON IN VITRO

  • Received:2017-01-12 Revised:2017-01-12 Online:1986-05-31 Published:2017-01-12

摘要: 用扫描电镜和透射电镜观察了猪囊尾蚴经吡喹酮(200μg/ml与400μg/ml)作用不同时间(5、30、60分钟)后的变化.在扫描电镜下可见其颈部微绒毛出现粘连、脱落,表面布满泡状物,头部吸盘中央也出现泡状物.在透射电镜下可见局部皮层呈空泡化,基底膜变宽,肌层肿胀,合体细胞疏松。

关键词: 猪囊尾蚴, 吡喹酮, 电镜观察, 基底膜, 微绒毛, 合体细胞, 扫描电镜, 泡状物, 头颈部, 皮下肌

Abstract: The changes of Cysticercus cellulosae treated in vitro with pyquiton were studied under the transmission and scanning electron microscopes. They were also compared with normal controls. The detachment and adhesion of microtriches on the neck of their scolex were demonstrated under scanning electron microscope and numerous vesicular structures were seen on the surface of their neck. The vacuolization of their tegument, swelling of muscles and finally, destruction of their tissues were seen under the transmission electron microscope. It is indicated that pyquiton has a direct destructive effect on the parasite.