中国寄生虫学与寄生虫病杂志 ›› 1985, Vol. 3 ›› Issue (3): 178-180.

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吡喹酮对日本血吸虫表皮作用的扫描电镜观察

杨士静,李宛,苏信生   

  1. 上海第二医学院寄生虫学教研室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1985-08-31 发布日期:2017-01-12

SCANNING ELECTRON MICROSCOPY OF THE EFFECT OF PYQUITON ON THE TEGUMENT OFSCHISTOSOMA JAPONICUM

  • Received:2017-01-12 Revised:2017-01-12 Online:1985-08-31 Published:2017-01-12

摘要: 用单剂吡喹酮治疗感染日本血吸虫小鼠,分别在6、12、24、48小时取成虫,用扫描电镜观察,发现虫体表皮(外皮层)产生肿胀和皱缩、球状感觉乳突凹陷、表皮大面积糜烂等变化,在同一宿主的不同虫体之间以及同一虫体的不同部位间的损伤强度存在着差异。

关键词: 日本血吸虫, 扫描电镜观察, 感觉乳突, 吡喹酮, 抱雌沟, 药物作用, 寄生虫学, 海绵状, 腹吸盘, 日本血吸虫成虫

Abstract: The effect of a single-dose oral administration of pyquiton on the tegumental sur face of adult Schistosoma japonicum in infected mice (C57/BL) was studied by SEM. Worms were recovered from mice 6,12,24 and 48 hrs after treatment, respectively. Pronounced tegumental surface alterations were observed including swelling, wrinkling and constriction, collapse of sensory bulbs, erosion of large areas of the surface. Different types of lesions with different degrees of intensity were described among worms from the same individual host.