中国寄生虫学与寄生虫病杂志 ›› 1984, Vol. 2 ›› Issue (1): 13-16.

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日本血吸虫病血清流行病学研究——Ⅰ.三个不同流行区人群抗体反应的年龄分布调查

陈淑贞,吴观陵,许生,肖相祖,褚和生,郭镇泰,赵慰先   

  1. 南京医学院寄生虫学研究室; 南京医学院寄生虫学研究室; 南京医学院寄生虫学研究室; 江西省星子县血防站; 江苏省昆山县血防站; 江苏省无锡市郊区血防站; 南京医学院寄生虫学研究室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1984-02-28 发布日期:2017-01-12

SEROEPIDEMIOLOGY OF SCHISTOSOMIASIS JAPONICA I.AGE DISTMBUTION OF ANTIBODY RESPONSE IN POPULATIONS LIVING IN THREE AREAS OF DIFFERENT ENDEMICITY

  • Received:2017-01-12 Revised:2017-01-12 Online:1984-02-28 Published:2017-01-12

摘要: 本文报道了应用日本血吸虫肠相关抗原的间接血凝试验(IHA),对一个现存的和两个已经基本控制传播的血吸虫病流行区人群进行血清流行病学的调查结果。发现现存的流行区的人群抗体水平较其他两个地区明显为高。而且三个地区人群抗体阳性者的抗体滴度平均水平(GMRT)的年龄分布曲线也具不同的特征,现存流行区的低年龄组GMRT较高年龄组为高,而已经控制传播的地区低年龄组抗体水平则为0。认为分析当地低年龄组人群抗体水平,似可作为评价传播是否阻断的依据,并可作为监测流行趋势的工具。

关键词: 日本血吸虫病, 血清流行病学研究, 流行区人群, 抗体反应, 年龄组, 抗体阳性率, 年龄分布, 抗体水平, 血清学调查, 抗体滴度

Abstract: A study on seroepidemiology of schistosomiasis japonica was performed by means; of IHA test with a gut-associated antigen of the adult worms among populations in one actually endemic area and two previously endemic, but now controlled areas of the infection. To explore the relationship between the age distribution of antibody response and the transmission of schistosomiasis in populations living in these areas with different endemicity, the graphic distribution curves of antibody levels according to age grouping were drawn. The age distribution curves of antibody levels in populations studied showed different patterns. It was suggested that in a given area, the level of antibody response of individuals in the youngest or younger age group could more likely reflect transmission in recent time and the analysis of antibody level of low age groups could provide a basis for evaluating whether the transmission had been interrupted or not.