作者简介：蔡珍（1989-）,女,博士,助理研究员,从事蚊媒传染病防治研究。E-mail:
收稿日期: 2019-06-30
网络出版日期: 2019-11-07
基金资助
国家自然基金委杰出青年科学基金(No. 31825001)
Progress towards mosquito microbiome on regulating the transmission of mosquito-borne diseases
Received date: 2019-06-30
Online published: 2019-11-07
Supported by
Supported by National Science Fund for Distinguished Young Scholars (No. 31825001)
蔡珍 , 余茜 , 程功 . 蚊肠道微生物调节蚊媒传染病传播的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2019 , 37(5) : 603 -608 . DOI: 10.12140/j.issn.1000-7423.2019.05.017
Mosquito is a hematophagous insect which transmits malaria, dengue fever or Zika infections by blood feeding, posing fatal threats to global public health. Mosquito midgut is the first line of defense against infected pathogens. When mosquito feeds on a host with virus or parasite infections, the pathogens in the host blood are ingested into the midgut in which variant commensal microbes harbor. Some commensal microbes have effect on the infection of ingested pathgens into epithelial cells of mosquito midgut by secreting some proteins or other molecules, thereby regulating the process of pathogen transmission in the mosquito. In this review, we summarize research on the commensal microbes that regulate the transmission of mosquito-borne diseases and understand various mechanisms of commensal microbes involved in the transmission of mosquito-borne pathogens.
Key words： Mosquito microbiota; Mosquito-borne disease; Transmission
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