收稿日期: 2023-01-14
修回日期: 2023-02-15
网络出版日期: 2023-04-21
基金资助
国家自然基金面上项目(81572020)
Research advances of the immune regulation of helminths and their derived molecules on mite-induced asthma
Received date: 2023-01-14
Revised date: 2023-02-15
Online published: 2023-04-21
Supported by
National Natural Science Foundation of China(81572020)
李文杰 , 冯萌 , 程训佳 . 蠕虫及其来源分子对螨性哮喘免疫调控的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2023 , 41(2) : 131 -136 . DOI: 10.12140/j.issn.1000-7423.2023.02.001
With the improvement of living hygiene, the helminth infection rate has declined, and people have entered the post-parasite stage. But at the same time, the incidence rate of mite-induced asthma is increasing, which has caused a significant social and economic burden. Increasing evidence showed a correlation between helminth infection and allergy. This article reviews the regulation of helminth and their derived molecules on the occurrence and development of mite-induced asthma, including the direct regulation of antigen-presenting cells, humoral immunity, cellular immunity, release and action of cytokines, and the indirect regulation by regulating intestinal microflora, providing new ideas and directions for the treatment of mites-induced asthma.
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