收稿日期: 2021-03-28
修回日期: 2021-04-25
网络出版日期: 2021-11-10
基金资助
国家自然科学基金(82072303);国家寄生虫资源库(NPRC-2019-194-30);海南省重点研发计划项目(ZDYF2020120);海南省院士创新平台科研专项项目(YSCX202110);海南省重大科技计划项目(ZDKJ202003)
Application of metabolomics in research of medical helminths
Received date: 2021-03-28
Revised date: 2021-04-25
Online published: 2021-11-10
Supported by
National Natural Science Foundation of China(82072303);National Parasitic Resources Center of China(NPRC-2019-194-30);Key Research and Development Program of Hainan Province(ZDYF2020120);Specific Grant of Academician Innovation Platform of Hainan Province(YSCX202110);Major Science and Technology Program of Hainan Province(ZDKJ202003)
胡玥 , 吕志跃 . 代谢组学在医学蠕虫研究中的应用[J]. 中国寄生虫学与寄生虫病杂志, 2021 , 39(5) : 703 -709 . DOI: 10.12140/j.issn.1000-7423.2021.05.020
Metabolomics is a new type of omics that rapidly developed after genomics, transcriptomics and proteomics. Because of its unique advantages, metabolomics has been applied in early diagnosis of diseases, discovery of drug targets, and for understanding animal and plant metabolisms. Metabolomics has been increasingly using in studies of paras ites, focusing on parasites’ metabolism, screening diagnostic biomarkers and revealing mechanism of drug actions, to provide new ideas for exploring parasite-host interaction, and for further understanding of diagnosis and treatment of parasitic diseases. In this review, we summarize metabolomics associated research methodologies, and advances of their applications in studies of medical helminths, to provide reference for wider application of metabolomics in parasitology research.
Key words： Medical helminths; Metabolomics; Current applications
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