收稿日期: 2019-10-22
网络出版日期: 2020-09-09
基金资助
2019年上海健康医学院师资人才百人库项目(B1-0200-19-311143)
Advances in research on the roles of natural killer T cells in immune responses to parasitic infections
Received date: 2019-10-22
Online published: 2020-09-09
Supported by
Hundred Talents Project of Shanghai University of Medicine & Health Sciences in 2019(B1-0200-19-311143)
刘毅 , 蔡玉春 , 陈韶红 , 陈家旭 . 自然杀伤T细胞在寄生虫感染免疫中作用的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2020 , 38(4) : 477 -481 . DOI: 10.12140/j.issn.1000-7423.2020.04.014
Natural killer T(NKT) cells are a type of innate immune cells that express both T cell and NK cell surface markers. The cytokines secreted by NKT cells upon activation possess some properties that affect the adaptive immunity, thus bridging innate and adaptive immunity and playing important roles in anti-infection processes, tumor immunity and autoimmune diseases. NKT cells also play an important role in bridging innate and adaptive immunity during immune responses to parasitic infections. However, little research has been conducted in this field. In this article, the roles of NKT cells in immune responses to Leishmania, Plasmodium, Trypanosoma and Schistosoma infections are reviewed.
Key words： Parasite infection; Natural killer T cells; Immunity
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