中国寄生虫学与寄生虫病杂志 ›› 1994, Vol. 12 ›› Issue (4): 300-302.

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溴氰菊酯药浴阳性鼠阻断内脏利什曼病传播的实验研究

金长发,熊光华,洪玉梅,苏忠伟   

  1. 中国预防医学科学院寄生虫病研究所
  • 出版日期:1994-11-30 发布日期:2017-01-06
  • 基金资助:
    中华人民共和国卫生部科研基金

STUDIES ON THE EFFECT OF DELTAMETHRIN BATH TREATMENT OF HAMSTERS INFECTED WITH LEISHMANIA DONOV ANI FOR INTERRUPTING KALA-AZAR TRANSMISSION

  • Online:1994-11-30 Published:2017-01-06

摘要: 用中华白蛉分别饲吸两组染有杜氏利什曼原虫的背纹仓鼠(Cricetulusbarabensis),一组系经澳氰菊酯药浴后9-45d的仓鼠,另一组系未经药浴的仓鼠。实验结果表明饲吸药浴鼠的白岭在24h内全部中毒致死,饲吸未经药浴鼠的白蛉存活率很高。在剖检的吸血白蛉中,有69.1%的白蛉,在其消化道内发现有前鞭毛体的感染,这些前鞭毛体不仅在白蛉消化道内发育良好,且随饲吸时间的推移,前鞭毛体侵入食道、咽和喙部。背纹仓鼠是杜氏利什曼原虫理想的保虫宿主,经药浴的仓鼠进行人工感染,已失去感染能力。

关键词: 杜氏利什曼原虫, 中华白蛉, 溴氰菊酯, 背纹仓鼠

Abstract: Phlebotomus chinensis were fed respectively on two groups of Cricetulus barabensis infect-ed with Leishmania donovani,of which one group had received deltamethrin bath and theother was not treated with insecticide bath.The results showed that all the sandflies in the former group died within 24 hours,whilethose in the latter group had a high survival rate. Among the 165 sandflies examined,114(69.1%)became infected.The promastigotes not only developed well in the midgut,but alsoinvaded esophagus,pharynx and proboscis.In the control group,the mortality of sandfliesin 24 hours was 5.1%(3/59).According to the data obtained in the present study,the authors consider that insecticidebath treatment of infected domestic dogs in endemic villages could be used for interruptingkala-azar transmission.

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