中国寄生虫学与寄生虫病杂志 ›› 2012, Vol. 30 ›› Issue (3): 19-245-246.

• 研究简报 • 上一篇    下一篇

紫皮独蒜液对日本血吸虫尾蚴和钉螺的杀灭效果

杨蓬,段红颜,王策,孙金连,李成诚,王庆丽,沈祥志,王龙,董兴齐,杨毅梅*   

  1. 大理学院临床医学院08级3班,大理 671000
  • 出版日期:2012-06-30 发布日期:2012-09-28

Killing Effect of Garlic Extract on Schistosoma japonicum cercariae and Oncomelania snails

YANG Peng, DUAN Hong-yan, WANG Ce, SUN Jin-lian, LI Cheng-cheng, WANG Qing-li, SHEN Xiang-zhi, WANG Long, DONG Xing-qi, YANG Yi-mei*   

  1. Faculty of Clinical Medicine,Dali University,Dali 671000,China
  • Online:2012-06-30 Published:2012-09-28

摘要: 解剖镜下观察不同浓度紫皮独蒜液(下称蒜液)杀灭日本血吸虫(Schistosoma japonicum)尾蚴和钉螺(Oncomelania)的效果,并记录所需时间;用日本血吸虫尾蚴感染皮肤已涂抹不同浓度蒜液的小鼠,计算感染率。另设去离子水对照组。结果,蒜液原液杀灭血吸虫尾蚴的平均时间为(77.33±25.01) s,浓度为0.79%~50.00%蒜液杀死日本血吸虫尾蚴的平均时间为(299.67±18.96)~(73.00±1.73) s,而对照组中尾蚴在600 s内一直有活力;蒜液原液在1 d内可全部杀灭钉螺,而对照组钉螺2 d内死亡率为0;皮肤涂抹不同浓度的蒜液的小鼠感染率均为0,对照组小鼠感染率则为100%。表明蒜液有较好的杀灭日本血吸虫尾蚴和钉螺的效果,涂肤具有防御日本血吸虫尾蚴感染的作用。

关键词: 紫皮独蒜, 日本血吸虫, 尾蚴, 钉螺

Abstract: The killing effect of different concentrations of garlic extract solution on Schistosoma japonicum cercariae and Oncomelania snails was observed under dissecting microscope. Mice were infected by cercariae through the abdominal skin daubed by garlic solution or by deionized water as control. The results showed that the cercariae were killed in (77.33±25.01) s in average, it needed (73.00±1.73)-(299.67±18.96) s under the garlic solution concentrations of 50.00%- 0.79% respectively, while the cercariae kept alive in 600 s in the control. The snails were killed in 1 d by 100% garlic solution but no death in the control in 2 d. No mouse daubed with different concentrations of garlic solution was found infected by schistosomes while 100% of the control mice got infected. It is concluded that the garlic shows satisfactory effect in killing cercariae and Oncomelania snails, and may prevent schistosome infection by daubing the skin.

Key words: Garlic, Schistosoma japonicum, Cercariae, Oncomelania snails