驱动血吸虫生长发育的干细胞研究进展

doi:10.12140/j.issn.1000-7423.2022.04.003

中国寄生虫学与寄生虫病杂志 ›› 2022, Vol. 40 ›› Issue (4): 436-440.doi: 10.12140/j.issn.1000-7423.2022.04.003

驱动血吸虫生长发育的干细胞研究进展

王吉鹏^*()

复旦大学生命科学学院遗传工程国家重点实验室,上海 200438

收稿日期:2022-04-27 修回日期:2022-05-30 出版日期:2022-08-30 发布日期:2022-09-07
通讯作者: 王吉鹏
作者简介:王吉鹏（1986-）,男,博士,研究员,从事血吸虫发育生物学及抗虫药物研究。E-mail： jipengwang@fudan.edu.cn
基金资助:
国家重点研发计划(2021YFC2300800);国家重点研发计划(2021YFC2300803)

Research progress of stem cells in driving schistosome growth and development

WANG Ji-peng^*()

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China

Received:2022-04-27 Revised:2022-05-30 Online:2022-08-30 Published:2022-09-07
Contact: WANG Ji-peng
Supported by:
National Key Research and Development Program of China(2021YFC2300800);National Key Research and Development Program of China(2021YFC2300803)

摘要/Abstract

摘要：

干细胞是一类可以增殖和分化的细胞,具有组织更新及损伤修复等功能。近年来,干细胞在血吸虫及其他寄生扁虫中的功能研究受到关注并取得重要进展。本文总结了血吸虫干细胞领域的研究进展及主要研究方法和工具,以期为深入理解血吸虫生长发育和寄生的生物学基础提供借鉴。

关键词: 血吸虫, 干细胞, 细胞分化, 组织更新, 生长发育

Abstract:

Stem cells are unspecialized cells that have the ability of self-renewal and differentiation into multiple cell types, which commit the tissue turnover and repair of the body. In recent years, the function of stem cells in schistosomes and other parasitic flatworms has attracted attention and a series of discoveries have been made. This review summarized the advances and tools in schistosome stem cell research to provide valuable information for understanding the basic biology of schistosome growth and development as well as the establishment of intermediate and definitive hosts.

Key words: Schistosoma, Stem cell, Cell differentiation, Tissue turnover, Growth and development

中图分类号:

R383.24

王吉鹏. 驱动血吸虫生长发育的干细胞研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(4): 436-440.

WANG Ji-peng. Research progress of stem cells in driving schistosome growth and development[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2022, 40(4): 436-440.

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驱动血吸虫生长发育的干细胞研究进展

Research progress of stem cells in driving schistosome growth and development

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