中国寄生虫学与寄生虫病杂志

• 学术争鸣 • 上一篇    下一篇

弓形虫病的若干术语释义及实验室诊断的解读与处置策略

沈继龙*   

  1. 安徽医科大学病原生物学教研室, 安徽病原生物学省级实验室, 安徽省人兽共患病重点实验室, 合肥230032
  • 出版日期:2017-08-30 发布日期:2017-09-14

Interpretations of terms used in toxoplasmosis and clinical implications of serodiagnosis and treatment strategy

SHEN Ji-long*   

  1. Department of Parasitology, Anhui Medical University; Provincial Laboratory of Pathogen Biology; Anhui Provincial Laboratory of Zoonoses; Hefei 230032, China
  • Online:2017-08-30 Published:2017-09-14

摘要:

免疫力正常的个体获得性弓形虫感染常无明显临床表现而呈慢性感染。隐性感染活化引起的弓形虫病是包括艾滋病等免疫功能受损患者常见的甚至致死性的并发感染疾病。孕妇的急性弓形虫感染可导致严重的不良妊娠结局。本文针对我国行业标准《弓形虫病的诊断》(WST 486-2015)的若干术语概念以及实验室检测指标判读的困惑进行试解析, 并介绍了国外孕妇弓形虫感染的实验室检测以及处置方案, 旨在为我国弓形虫病防治提供参考。

关键词:  弓形虫病, 血清学诊断, 易感性, 先天性弓形虫病

Abstract:

Toxoplasma infection in immunocompetent individuals is usually asymptomatic with chronic infection. But in immunocompromised individuals including patients with HIV/AIDS, the reactivation of latent infection may cause severe even fatal complications. Acute Toxoplasma infection in pregnant women may result in serious adverse outcomes. This review tries to interpret several terms used in the WS/T 486-2015 Diagnosis of Toxoplasmosis standard and the laboratory test indicators. It also introduces the laboratory diagnosis of toxoplasmosis in pregnancy in other countries and the treatment schemes, so as to provide reference for toxoplasmosis prevention and treatment in China.

Key words: Toxoplasmosis, Serodiagnosis, Pregnancy, Congenital infection