中国寄生虫学与寄生虫病杂志 ›› 2006, Vol. 24 ›› Issue (3): 10-203.

• 实验报道 • 上一篇    下一篇

密达利杀灭湖北钉螺效果的研究

朱丹1;周晓农1;张世清2;张功华2;刘和香1;吕大兵2;蔡国英1;倪全珍1;操治国2;吴维铎2   

  1. 1 中国疾病预防控制中心寄生虫病预防控制所, 世界卫生组织疟疾、血吸虫病和丝虫病合作中心, 上海 200025;2 安徽省寄生虫病防治研究所, 芜湖 241000
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2006-06-30 发布日期:2006-06-30

Study on the Molluscicidal Effect of META-Li Against Oncomelania hupensis

ZHU Dan1;ZHOU Xiao-nong1;ZHANG Si-qing2;ZHANG Gonghua2;LIU He-xiang1;LU Da-bing2;CAI Guo-ying1;NI Quan-zheng1;CAO Zhi-guo2;WU Wei-duo2   

  1. 1 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China; 2 Anhui Institute of Parasitic diseases, Wuhu 241000, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-06-30 Published:2006-06-30

摘要: 目的 实验室和现场试验评价密达利(META-Li, 40%四聚乙醛水乳剂)杀灭湖北钉螺的效果。 方法 室内:采用泥缸喷洒法、烧杯浸杀法和三角沉淀杯上爬法,用敲击法观察不同时间、不同浓度密达利对湖北钉螺的杀灭和抑制上爬作用。现场:选择安徽省芜湖县草滩进行现场喷洒试验,密达利剂量为1、2和4 g/m2,设氯硝柳胺药物对照剂量为1 g/m2和清水空白对照组,观察施药后3、7和15 d检查钉螺存活情况。 结果 室内喷洒试验:24、48和72 h的半数致死剂量(LD50)分别为0.78、0.44和0.46 g/m2;室内浸杀试验:24、48、72 h的半数致死浓度(LC50)分别为44.4、27.4和24.8 mg/L;24 h抑制钉螺上爬半数有效浓度(EC50)为5.86 mg/L。现场喷洒试验:密达利2 g/m2喷洒后7 d钉螺死亡率大于90%,灭螺效果和氯硝柳胺1 g/m2相当(P>0.05)。 结论 密达利室内及现场喷洒灭螺效果明显,有抑制钉螺上爬作用。

关键词: 密达利, 四聚乙醛, 钉螺, 杀螺剂

Abstract: Objective To evaluate the molluscicidal effect of the META-Li(40% META liquid formulation) against Oncomelania snails in laboratory and field. Methods The experiment of META-Li against the snails by spraying, immersion and climbing-inhibition test was carried out in laboratory. Spray method was performed in the field to compare with the wettable powder of 50% niclosamide ethanolamine salt. Results In laboratory, the LC50 of META-Li by spraying for 1, 2, 3 days was 0.78, 0.44 and 0.46 g/m2 respectively; by immersion method for 1, 2, 3 days, it was 44.4, 27.4 and 24.8 mg/L respectively. When sprayed with active ingredient 2 g/m2 of META-Li in the field, the snail death rate was above 90% after 7 days, similar to that of niclosamide. Conclusion META-Li shows high molluscicidal and climbing-inhibition effect on Oncomelania snails.

Key words: Meta-Li, Metaldehyde, Oncomelania hupensis, Molluscicide