中国寄生虫学与寄生虫病杂志 ›› 1991, Vol. 9 ›› Issue (1): 35-38.

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实验性肝阿米巴病的病理组织学观察

余涌,连惟能   

  1. 上海医科大学寄生虫学教研室
  • 出版日期:1991-02-28 发布日期:2017-01-09
  • 基金资助:
    国家自然科学基金(项目编号:386C958)

HISTOPATHOLOGY OF EXPERIMENTAL HEPATIC AMEBIASIS

  • Online:1991-02-28 Published:2017-01-09

摘要: 应用肝内接种法建立实验性肝阿米巴病金黄仓鼠模型。观察肝阿米巴病的病理形态,其大体标本可分为孤立型、多结节型和破溃型3种脓肿类型。光镜观察变质性病变和增生性病变可分别显示早、晚期肝阿米巴病的病理组织学特性。本文探讨了肝阿米巴病的发展和溶组织内阿米巴的致病机制。

关键词: 溶组织内阿米巴, 肝阿米巴病, 病理组织学, 金黄仓鼠

Abstract: The method of intrahepatic inoculation was successfully used to establish an experimental model of hepatic amebiasis in golden hamsters for studying its pathological morphology. Three types of macroscopic liver lesions, i. e. isolated abscess, multinodular abscess and ruptured lesion were described. On light microscopy the alteration and the proliferation type lesions were found as distinct pathological characteristics of the early and advanced hepatic amebiasis respectively. The developmant pattern of hepatic amebiasis and the pathogenicity of Entamoeba histolytica were discussed.