中国寄生虫学与寄生虫病杂志 ›› 1990, Vol. 8 ›› Issue (3): 217-219.

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肺螨症的临床观察及其治疗的研究

陈兴保,孙新,胡守锋   

  1. 蚌埠医学院
  • 收稿日期:2017-01-09 修回日期:2017-01-09 出版日期:1990-08-31 发布日期:2017-01-09

CLINICAL MANIFESTATION AND TREATMENT OF PULMONARY ACARIASIS

  • Received:2017-01-09 Revised:2017-01-09 Online:1990-08-31 Published:2017-01-09

摘要: 调查与粮食和中药材密切接触者363人,其中65例肺螨症患者痰螨检查阳性。具有咳嗽、痰多、痰中带血、胸闷、胸痛、气急、乏力、低热等临床症状。胸片示肺门特征性结节状阴影。患者血清特异性抗体阳性,嗜酸粒细胞增高。所有患者均采用甲硝达唑治疗3个疗程,治疗量为0.2g每日3次,或0.4g每日2次,疗程7d,每疗程间隔7~10d,治后痰螨阴转率达94.4%,多数患者临床症状的X线胸片有明显改善,嗜酸粒细胞降至正常范围,提示对肺螨症有明显的疗效。

关键词: 肺螨症, 临床观察, 甲硝达唑治疗

Abstract: A survey on pulmonary acariasis was carried out in the grain store and in the Chinese medicinal herb plant. Of 363 persons examined, 92(25.3%) were mites-positive in their sputum. 65 of them had symptoms and signs attributed to pulmonary acariasis, the incidence being 17.9%. The main clinical manifestations were productive cough, hemoptysis, chest pain, dyspnea asthma and marked eosinophilia. Roentgenogram of these cases revealed widening hilum shadow, increased and disordered lung markings, multiple cloudy shadow and nodular opacities ranging from 1-5mm in diameter scattered throughout the lower field of lungs.All the patients were treated with three courses of metronidazole. In each course a daily dose of 0.6g (0.2g tid) or 0.8g (0.4g bid) was given orally for seven days with an interval of 7-10 days between two courses. After three courses, the clinical manifestations and radiographic findings were much improved in most cases, eosinophilia, dropped to normal limit, mites disappeared from sputum in 94.4% of patients. All these showed that metronidazole is rather effective in treating pulmonary acariasis;