中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (2): 141-143.

• • 上一篇    下一篇

阿苯哒唑治疗囊虫病300例的临床观察

刘德惠,刘淑珍,张永江,李书森,郎志谨,王永才,李福文,葛继先,赵景才   

  1. 吉林农业大学囊虫病防治研究所; 吉林农业大学囊虫病防治研究所; 吉林省柳河县囊虫病医院; 吉林省扶余县第二医院; 大连医学院附属医院; 吉林省柳河县囊虫病医院; 大连医学院附属医院; 吉林省柳河县囊虫病医院; 吉林省扶余县第二医院
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1987-05-31 发布日期:2017-01-12

CLINICAL OBSERVATION ON TREATMENT OF 300 CASES OF CYSTICERCOSIS WITH ALBENDAZOLE

  • Received:2017-01-12 Revised:2017-01-12 Online:1987-05-31 Published:2017-01-12

摘要: 应用阿苯哒唑治疗囊虫病300例,其中脑型175例,皮下肌肉型125例。阿苯哒唑采用15~20mg/kg/d,分2次口服,10d为一疗程,共3个疗程;疗程间隔15~21d。治疗后6~12个月,根据体表囊虫结节数、虫体变化、神经症状及体征、脑CT表现、智力与劳动能力恢复情况判定疗效。结果皮下肌肉型患者的治愈率为64%,显效率为25.6%,改善率为10.4%:脑型患者治愈率为40.6%,显效率为44%,改善率为15.4%。不良反应较少,较轻,未发现无效病例及因副反应而中止疗程者。

关键词: 脑囊虫病, 阿苯哒唑, 临床观察, 皮下肌, 囊虫结节, 活力试验, 吉林省, 随访检查, 治疗后, 神经症状

Abstract: Three hundred cases of cysticercosis cellulosae (175 cerebral, 125 subcutaneous-muscular) were treated orally with albendazole, 15-20 mg/kg/day for a 10-day course. Every patient received 3 treatment courses with an interval of two or three weeks.After 6-12 months, the therapeutic effect of albendazole was estimated in subcutaneous-muscular cases by the number of subcutaneous nodules, the activity and the morphological change of larvae in cerebral cases by the neuropsychic symptoms, CSF changes, CT findings and the degrees of recovery in physical and mental ability.The result showed that in the cases of subcutaneous-muscular cysticercosis the cure rate was 64.0%;the rate of significant effect, 25.6%; and that of clinical improvement, 10.4%; while in the cases of cerebral cysticercosis the rates were 40.6, 44.0 and 15.4%, respectively.