中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (1): 51-52.

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云南人猪肉孢子虫动物感染实验

连自强,许聪恩,戴丽华,金翠仙,周镇炳,李文泰,左仰贤,陈福强   

  1. 云南大理州血吸虫病防治研究所; 云南大理州血吸虫病防治研究所; 云南大理州血吸虫病防治研究所; 云南大理州血吸虫病防治研究所; 云南大理州血吸虫病防治研究所; 云南大理州血吸虫病防治研究所; 云南大学生物系; 云南大学生物系
  • 出版日期:1987-02-28 发布日期:2017-01-12
  • 基金资助:
    中国科学院科学基金

EXPERIMENTAL INFECTION OF SARCOCYSTIS SUIHOMINIS IN PIGS

  • Online:1987-02-28 Published:2017-01-12

摘要: 从吃生猪肉的人粪便分离收集孢子囊接种猪,56d后在猪的心肌和骨骼肌中发现肉孢子虫包囊。包囊呈梭状、椭圆或长椭圆形。包囊壁有密集绒毛状突起,并由壁向内形成隔膜将包囊分隔成许多隔室,室中充满香蕉形缓殖子,其大小为10.46×4.61μm。有些包囊中有圆形或近圆形母细胞。用含包囊的生猪肉感染猕猴5只,未成功;但感染前肌注氢化可的松的1只猴在感染后第11d开始排出孢子囊,孢子囊大小为12.72×10.24μm,持续9天。

关键词: 动物感染实验, 肉孢子虫, 血吸虫病防治, 云南大学, 恒河猴, 大理州, 化可的松, 生猪肉, 组织切片, 实验感染

Abstract: Sporocysts of Sarcocystis suihominis collected from feces of infected persons who had ingested raw pork were used to infect swines. On the 56th day post inoculation, cysts were found in the cardiac and skeletal muscles. The cysts are spindle-like, elongated or elliptic. The cyst wall had numerous thick, villi-like projections and the cysts wera divided into many compartments by septa formed from the cyst wall. Each compartment was filled with banana-like bradyzoites, measuring 10.46×4.61 μm. Some of the cysts-had spherical or spheroidal metrocysts.Five rhesus monkeys fed raw pork containing S. suihominis cysts were not infected, while another monkey which had received hydrocortisone injection two days before S. suihominis intubation for 5 days voided sporocysts from feces on the eleventh day post inoculation for a period of 9 days. The sporocysts measured 12.72×10.24 μm.