中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (1): 29-31.
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黄美玉,连惟能
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摘要: 本文观察了替硝唑(Tinidazole)对体外培养的两株阴道毛滴虫和一株人毛滴虫的作用.该药与阴道毛滴虫共同培养,48h的100%致死浓度为20μg/ml,在2μm/ml浓度时,有一定程度的抑制作用;与甲硝唑对比,替硝唑的作用低一个稀释度。该药与人毛滴虫共同培养,48h的100%致死浓度为20μg/ml,在4μg/ml浓度时,有一定程度的抑制作用,与甲硝唑对比,作用相同。
关键词: 阴道毛滴虫, 替硝唑, 效果观察, 人毛滴虫, 替硝哇, Tinidazole, 抑制作用, 滴虫性, 药物化学, 阴道炎
Abstract: The trichomonadicidal activity of tinidazole (Fasigyn) was evaluated by the ire vitro cultivation of Trichomonas vaginalis and Trichomonas hominis with different drug concentrations. The results showed that, after 48-hour incubation with tinidazole, the 100% lethal concentration was 20μg/ml. The trichomonadicidal effect of tinidazole was one titre lower than that of metronidazole. With regard to T. hominis, after 48-hour incubation with tinidazole, the 100% lethal concentration was 20μg/ml. In comparison with metronidazole, the trichomonadicidal effect of tinidazole was similar.
黄美玉,连惟能. 替硝唑体外抗毛滴虫效果观察[J]. 中国寄生虫学与寄生虫病杂志, 1987, 5(1): 29-31.
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