中国寄生虫学与寄生虫病杂志 ›› 1985, Vol. 3 ›› Issue (2): 117-119.

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大劣按蚊对约氏疟原虫敏感性的观察

宋宗臣,刘连珠,冯崇英,陈福珍,黄复生,刘丽娟   

  1. 第三军医大学寄生虫学教研室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1985-05-31 发布日期:2017-01-12

OBSERVATION ON THE SUSCEPTIBILITY OF ANOPHELES DIRUS TO PLASMODIUM YOELII YOELII

  • Received:2017-01-12 Revised:2017-01-12 Online:1985-05-31 Published:2017-01-12

摘要: 以斯氏按蚊传代保种的约氏疟原虫(BY265株)接种小鼠后第3、4天感染大劣按蚊,涎腺感染率为4.88%,进腺子孢子数少于10个。约氏疟原虫经过大劣按蚊传代后,大劣按蚊的涎腺感染率明显增高。感染蚊传3、4、6和7代首次血传的疟原虫,涎腺感染率分别为31.7%(13/41)、70%(14/20)、6.9%(2/29)和30%(6/20)。以含有第6代子孢子的大劣按蚊叮咬小鼠,能使鼠获得感染,第7代疟原虫感染的大劣按蚊涎腺内子孢子数可超过2,000个。结果表明约氏疟原虫对大劣按蚊有逐渐适应的能力。

关键词: 大劣按蚊, 约氏疟原虫, 感染率, 疟原虫感染, 第三军医大学, 斯氏按蚊, 寄生虫学, 涎腺, 感染度, 昆明株小鼠

Abstract: We had reported previously that when A. dims was fed on mice (Kunming strain) infected with Plasmodium yoelii yoelii (BY265 strain), the infection rate of salivary gland 3 and 4 days later was only 4.88%. In this paper we reported the increasing tendency of infection rates after several successive passages. The infection rate of salivary glands for the 3rd, 4th, 6th and 7th generations from the first blood passage was 31.7%, 70.0%, 6.9% and 30.0% respectively. Among 7 mice bitten by A, dims containing sporozoites of the 6th generation in their salivary glands two mice became infected. The number of sporozoites was over 2,000 in the salivary glands of A. dims when they were fed on mice with parasites of the 7th generation. The results suggested that there might be some adaptative selection of P. yoelii yoelii to A. dims.