中国寄生虫学与寄生虫病杂志 ›› 1985, Vol. 3 ›› Issue (1): 27-28.

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晚期血吸虫病患者血清补体C_4的变化及其意义

屠聿脩,黄湘虎,童明庆,王瑞云,陈锺英   

  1. 南京医学院第一附属医院传染病科
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1985-02-28 发布日期:2017-01-12

CHANGE IN SERUM C_4 AND ITS SIGNIFICANCE IN PATIENTS WITH LATE SCHISTOSOMIASIS JAPONICA

  • Received:2017-01-12 Revised:2017-01-12 Online:1985-02-28 Published:2017-01-12

摘要: 本文对30例晚期血吸虫病患者进行了血清C_4、C_3与循环免疫复合物(CIC)的检测,发现:(1)晚血患者C_4水平较正常人降低,提示有补体经典途径的激活;(2)晚血患者CIC水平增高,并且C_4与CIC呈负相关;提示C_4的降低是由于被免疫复合物激活所致;(3)研究晚血的补体经典途径的活化,C_4优于C_3。

关键词: 晚期血吸虫病, 补体C_, 循环免疫复合物, 患者血清, 传染病科, 补体经典途径, 标准曲线, 附属医院, 免疫扩散法, 发病机理

Abstract: The level of the serum C4, C3 and CIC was determined in 30 cases of late schistosomiasis. It was found that: (1) the level of C4 was lower in the patients than that innormal individuals, suggesting that activation of the classical pathway of complementdid occur in late schistosomiasis; (2) the level of CIC was elevated in the patienis,being negatively correlated with C4. C4 other than C3 is recommended for studying' the activation of classical pathway of complement in late schistosomiasis.