中国寄生虫学与寄生虫病杂志 ›› 2021, Vol. 39 ›› Issue (4): 505-513.doi: 10.12140/j.issn.1000-7423.2021.04.014
收稿日期:
2020-10-16
修回日期:
2021-01-22
出版日期:
2021-08-30
发布日期:
2021-08-11
通讯作者:
沈玉娟
作者简介:
孙叶挺(1997-),男,硕士研究生,从事寄生虫感染免疫研究。E-mail: 18863665089@163.com
基金资助:
SUN Ye-ting(), CAO Jian-ping, SHEN Yu-juan*()
Received:
2020-10-16
Revised:
2021-01-22
Online:
2021-08-30
Published:
2021-08-11
Contact:
SHEN Yu-juan
Supported by:
摘要:
髓源抑制性细胞(MDSC)是一群未成熟的异质性髓系细胞,是树突状细胞、巨噬细胞、粒细胞的前体。这些前体细胞在病理条件下可被募集到如淋巴结、脾脏、外周血及肿瘤微环境中,并进一步诱导活化。活化后的MDSC可以通过各种机制抑制T细胞免疫反应,广泛存在于寄生虫感染的各阶段。本文就MDSC在寄生虫感染领域免疫抑制功能的研究进展作一综述。
中图分类号:
孙叶挺, 曹建平, 沈玉娟. 髓源抑制性细胞免疫抑制功能及其在寄生虫感染领域的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(4): 505-513.
SUN Ye-ting, CAO Jian-ping, SHEN Yu-juan. Research progress on immunosuppressive function of myeloid-derived suppressor cells and its role in parasitic infection[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2021, 39(4): 505-513.
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