中国寄生虫学与寄生虫病杂志 ›› 1984, Vol. 2 ›› Issue (3): 185-187.

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血吸虫病患者外周血细胞超氧化物歧化酶活性的测定

匡天兴,杜泽民,王若霜,朱时钰,沈昂石 ,蒋士祥,徐琴秋,孙正德   

  1. 吴县血吸虫病防治站; 吴县血吸虫病防治站; 吴县血吸虫病防治站; 吴县血吸虫病防治站; 吴县血库; 吴县沙湖医院; 吴县沙湖医院
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1984-08-31 发布日期:2017-01-12

ASSAY OF SUPEROXIDE DISMUTASE ACTIVITY IN THE PERIPHERAL BLOOD CELLS OF PATIENTS WITH SCHSTOSOMIASIS

  • Received:2017-01-12 Revised:2017-01-12 Online:1984-08-31 Published:2017-01-12

摘要: 测定了各期血吸虫病患者与健康人的超氧化物歧化酶活力。结果;早期血吸虫病患者(19例)为983U/ml,晚期血吸虫病患者(43例)为486U/ml,晚期血吸虫病基本治愈者(9例)为617U/ml,健康人(30名)为1,411U/ml。统计处理表明健康人与晚期血吸虫病患者的酶活力有极显著差异(P0.001),早期血吸虫病患者与晚期血吸虫病患者的酶活力也有极显著差异(P0.001)。对超氧北物歧化酶在血吸虫病肝硬化发病机制中的作用进行了讨论。

关键词: 超氧化物歧化酶活性, 晚期血吸虫病, 外周血细胞, 血吸虫病肝硬化, SOD活性, 血吸虫病防治, 上腺素, 自由基, 自身氧化, 抽提液

Abstract: SOD activity levels in the peripheral blood cells of 19 cases of early schistosomia- sis, 43 cases of late schistosomiasis, 9 cases of late schistosomiasis who have been essentially cored and 30 cases of healthy persons wfere determined.The results showed that SOD activity is 98 3U in patients with early schisto-miasis, 486U in patients of late schistosomiasis, 617U in patients of late schistosomiasis who have been essentially cured, and 1,411U in healthy persons, respectively.There exists a significant difference between the SOD activity in normal healthy persons and in patients of late schistosomiasis (P0.001).