目的 分析2005-2018年连云港市输入性疟疾疫情趋势,探讨适合连云港市的输入性疟疾防控策略。方法 收集2005-2018年全市网报疟疾疫情、个案调查资料、健康干预等其他工作资料,用Epidata3.0录入数据,采用SPSS 17.0软件对资料数据和防控效果进行统计分析。结果 2005-2018年全市共报告输入性疟疾324例,期间有两个发病高峰,分别为2008年（30例）和2013-2015年（54例、42例、59例）,2016-2018年逐年下降（36例、22例、20例）;其中境外输入321例（99.1%）,省外输入3例（0.9%）;96.9%（314/324）的病例由非洲输入,主要来自赤道几内亚（123例,39.2%）,安哥拉（54例,17.2%）;所有病例皆为男性,年龄主要集中在40~49岁（45.1%,146/324）; 职业以务工人员为主（295例,91.0%）;一年四季皆有病例报告;其中恶性疟245例（75.6%）、间日疟14例（4.3%）、卵形疟47例（14.5%）、三日疟15例（4.6%）,混合感染3例（0.9%）。病例主要分布在东海县（152例,46.9%）和赣榆区（107例,33.0%）。初诊单位为疾控机构和医疗机构的病例数相同,均为156例（48.1%）。确诊单位以疾控机构为主,为201例（62.0%）。重症恶性疟病例12例,痊愈10例,死亡2例。对东海县、赣榆区等地615位赴境外高疟区务工人员和家属进行疟疾健康干预前后知识、态度及行为（KAP）调查,干预前后疟疾知识知晓率、态度正确率和行为良好率分别从19.7%、36.9%和76.6%上升至84.4%、88.0%和95.8%。结论 连云港市输入性疟疾疫情近年呈下降趋势。规范传染源管理,提高疟疾诊治能力,完善监测体系,加强对重点地区重点人群的健康教育是今后输入性疟疾防控的重点。

Objective To analyze the epidemic situation of imported malaria in Lianyungang, Jiangsu from 2005 to 2018, so as to formulate a better prevention and control strategy of malaria suitable for the area.Methods Information of malaria cases identified in Lianyungang from 2005 to 2018 were collected from Infectious Diseaes Report System of Disease Control and Prevention, Malaria Epidemic, Case Investigation Data, Public Helth Intervention and other related information. The malaria database was established using Epidata 3.0 and analyzed using SPSS17.0 software.Results Total 324 cases of imported malaria were reported from 2005 to 2018 in Lianyungang region with two peaks happened in 2008 (30 cases) and 2013-2015 (54, 42 and 59 cases, respectively). The incidence of imported malaria decreased since 2016 with 36 cases in 2016, 22 cases in 2017 and 20 cases in 2018. Almost all the cases (99.1%, 321/324) were imported from abroad, with only 3 cases (0.9%) were domestically imported from other provinces in China. For those imported cases, 96.9% of them were imported from Africa, of which 39.2% from Equatorial Guinea (123 cases) and 17.2% from Angola (54 cases). All cases were male, 45.1% of them were within the age of 40-49 years old (146 cases). Most of them (91.0%, 295/324) were the migrant workers returned from abroad. There was no seasonal difference of imported malaria cases. Total 75.6% (245/324) of them were infected with Plasmodium falciparum, 4.3% (14 cases) with P. vivax, 14.5% (47 cases) with P. oval, 4.6% with P.malariae (15 cases) and 0.9% (3 cases) were the mixed-infection. Donghai county contained the most cases (46.9%, 152/324), followed by Ganyu District (33.0%, 107/324). Half of the malaria cases seeked for the first medication at local CDC (156 cases) and half at the local medical institutions (156 cases), but most of the malaria cases received confirmed diagnosis at local CDC (62.0%, 201/324). Out of all imported cases, 12 were severe malaria with 2 cases died. A KAP survey (knowledge, attitudes and practices) on malaria was performed among the people who worked abroad at the high-risk malaria areas and their families members in Donghai County, Ganyu District and other places. After education and health intervention, the knowledge awareness rate for malaria prevention, the correct attitude rate and the good practice rate increased from 19.7%, 36.9% and 76.6% to 84.4%, 88.0%, and 95.8%, respectively.Conclusion The epidemic situation of imported malaria was declined in recent years in Lianyungang City. It is important to enhance the management of the infectious sources, improve the malaria diagnosis and treatment, and strengthen the health education of migrant workers and their families in order to achieve better prevention and control of imported malaria in the area.