病例报告

1例神经及皮下肌肉囊尾蚴病诊疗分析

  • 张艳 ,
  • 温杨 ,
  • 朱渝
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  • 1 四川大学华西第二医院小儿感染科, 出生缺陷与相关妇儿疾病教育部重点实验室, 四川成都 610041
    2 四川省成都京东方医院儿科, 四川成都 610219
张艳,女,硕士研究生,从事小儿内科工作。E-mail:18788927594@163.com
作者贡献

张艳负责文献搜索和论文撰写,温杨负责患者诊治、随访和资料收集,朱渝负责研究指导和论文修改。

* 朱渝(ORCID:0000-0001-8961-0136),女,博士,主任医师,从事儿童感染性疾病研究。E-mail:zhuyu_wj@163.com

收稿日期: 2025-11-17

  修回日期: 2026-01-09

  网络出版日期: 2026-04-13

基金资助

2022年国家临床重点专科建设项目(川卫医政函[2023]87号)

Diagnostic and therapeutic analysis of a case of cysticercosis involving the nervous system and subcutaneous muscles

  • ZHANG Yan ,
  • WEN Yang ,
  • ZHU Yu
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  • 1 Department of Pediatric Infectious Diseases, West China Second Hospital, Sichuan University; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, Sichuan, China
    2 Department of Pediatrics, Chengdu BOE Hospital, Chengdu 610219, Sichuan, China

Received date: 2025-11-17

  Revised date: 2026-01-09

  Online published: 2026-04-13

Supported by

2022 National Project for Clinical Key Specialty Development (Sichuan Health Commission Medical Administration Letter [2023] No. 87)

摘要

1例8岁藏族男性患儿,2024年10月25日以间断发热、头痛、呕吐收入四川大学华西第二医院。患儿长期居住于西藏自治区昌都市芒康县,家中饲养牛羊,有生食牛羊肉史。查体发现左侧上臂内侧近肘关节端可扪及一包块,大小为2 cm × 1.5 cm,无明显压痛;血清学检查示棘球蚴抗体IgG阳性;肝功能检查示谷丙转氨酶59 U/L,谷草转氨酶58 U/L;呼吸道病原体多重核酸检测示鼻病毒核酸阳性。10月29日、10月30日及11月6日粪样中均查见绦虫卵。头颅MRI(平扫 + 增强)示双侧大脑半球实质内多发占位,多发类圆形长T1长T2信号影;左上臂浅表超声示左侧肱二头肌肌层内囊实性占位。2024年11月1日予以左上臂皮下及肌肉结节切除,行病理活检,于肌肉及纤维组织内查见虫体,确诊为神经、皮下及肌肉囊尾蚴病。予阿苯达唑[15 mg/(kg·d)]联合吡喹酮[50 mg/(kg·d)]抗寄生虫治疗10 d,地塞米松抗炎治疗后好转出院,停药3 d后再次服药10 d。出院后3个月、6个月电话回访,均未见明显异常。

本文引用格式

张艳 , 温杨 , 朱渝 . 1例神经及皮下肌肉囊尾蚴病诊疗分析[J]. 中国寄生虫学与寄生虫病杂志, 2026 , 44(2) : 305 -307 . DOI: 10.12140/j.issn.1000-7423.2026.02.023

Abstract

A 8-year-old male Tibetan child was admitted to the West China Second Hospital of Sichuan University on October 25, 2024, due to intermittent fever, headache and vomiting. The patient had long resided in Mangkang County, Changdu City, Xizang Autonomous Region, with cattle and sheep raised in his family, and he had a history of consuming raw beef and mutton. Physical examination revealed a palpable mass near the elbow joint on the medial side of the left upper arm, measuring 2 cm × 1.5 cm with no significant tenderness. Serological tests showed positive IgG antibodies against Echinococcus, and liver function tests indicated alanine aminotransferase at 59 U/L and aspartate aminotransferase at 58 U/L. Respiratory multiplex pathogen nucleic acid assay tested positive for rhinovirus. Tapeworm eggs were identified in stool samples on October 29, October 30, and November 6. Head MRI scans (plain scan + contrast enhancement) displayed multiple space-occupying lesions in the bilateral cerebral hemispheres, presenting as circle-like long T1 and long T2 signal shadows, and superficial ultrasound of the left upper arm showed a cystic-solid mass within the muscular layer of biceps brachii. On November 1, 2024, a subcutaneous and intramuscular nodule resection was performed in the left upper arm, and pathological biopsy identified parasites in the muscle and fibrous tissues, which confirmed the diagnosis of neurocysticercosis, subcutaneous, and muscular cysticercosis. The child was given anti-parasitic treatment with albendazole [15 mg/(kg·d)] and praziquantel [(50 mg/(kg·d)] for 10 days, followed by anti-inflammatory therapy with dexamethasone. He had improvements and was then discharged from hospital. After discontinuation for 3 days, drug administration was resumed for another 10 days. Follow-up calls at 3 and 6 months post-discharge showed no significant abnormalities.

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