病例报告

鞭虫感染导致游走性肺炎1例

  • 莫骏 ,
  • 吴伟 ,
  • 陈颖
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  • 1 江苏省血吸虫病防治研究所, 江苏无锡 214064
    2 宜兴市人民医院, 江苏宜兴 214200
莫骏,男,硕士,主治医师,从事寄生虫感染诊疗。E-mail:671711181@163.com
*陈颖(ORCID:0000-0002-5666-6421),女,主管检验师,硕士,从事临床检验工作。E-mail: yeechanchan@163.com

收稿日期: 2025-08-18

  修回日期: 2025-11-07

  网络出版日期: 2026-02-24

基金资助

江苏省科教强卫工程项目,国家自然科学基金(82070123)

A case of migratory pneumonia caused by Trichuris trichiura infection

  • MO Jun ,
  • WU Wei ,
  • CHEN Ying
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  • 1 Jiangsu Institute of Parasitic Disease, Wuxi 214064, Jiangsu, China
    2 Yixing People’s Hospital, Yixing 214200, Jiangsu, China

Received date: 2025-08-18

  Revised date: 2025-11-07

  Online published: 2026-02-24

Supported by

Jiangsu Provincial Project of Invigorating Health Care through Science, Technology and Education and the National Natural Science Foundation of China(82070123)

摘要

13岁男性患儿因“食欲下降伴体质量不增半年余”,2025年7月1日就诊于江苏省血吸虫病防治研究所附属门诊部。多次查CT示肺部炎症,病灶呈游走性。血常规提示嗜酸粒细胞计数和百分比增加。血清学检测结果示多种寄生虫抗体阳性。使用改良加藤厚涂片法进行粪检,镜下可见纺锤形鞭虫虫卵。患儿为云南毕节人,有饮生水、生食史。结合患儿流行病学史、临床表现和相关检验结果,诊断为鞭虫感染引起的游走性肺炎。予患儿阿苯达唑(口服,200 mg/次,2次/d,连服3 d)治疗。服药后1周复查,血常规示嗜酸粒细胞下降,胸部CT示肺部炎症消退,粪检虫卵转阴。服药后2周患儿食欲明显改善,无其余不适。

本文引用格式

莫骏 , 吴伟 , 陈颖 . 鞭虫感染导致游走性肺炎1例[J]. 中国寄生虫学与寄生虫病杂志, 2026 , 44(1) : 148 -150 . DOI: 10.12140/j.issn.1000-7423.2026.01.023

Abstract

A 13-year-old male patient was admitted to the Outpatient Department of Jiangsu Institute of Parasitic Diseases on July 1, 2025, due to decreased appetite with no weight gain for more than half a year. Repeated CT scans showed pulmonary inflammation and migratory lesions. Routine blood tests showed an increased eosinophil count and percentage, and serological tests indicated positive antibodies against multiple parasites. Modified Kato-Katz thick smear technique of stool samples displayed spindle-shaped Trichuris trichiura eggs under a microscope. The case resided in Bijie, Yunnan Province, and had a history of consuming raw water and food. Migratory pneumonia caused by T. trichiura infection was diagnosed based on the patient’s epidemiological history, clinical manifestations and laboratory findings. The case was given albendazole by oral gavage (a single dose of 200 mg, twice daily for 3 consecutive days). Blood routine tests one week post-treatment showed a decrease in eosinophils, and chest CT scans displayed alleviated pulmonary inflammation, with no parasite eggs identified in stool samples. The patient’s appetite improved remarkably with no other discomfort 2 weeks post-treatment.

参考文献

[1] 陈云虹, 陈宝建, 李燕榕, 等. 3种土源性线虫虫卵体外发育形态学观察[J]. 海峡预防医学杂志, 2023, 29(6): 1-3, 36.
  Chen YH, Chen BJ, Li YR, et al. Morphological observations on the in vitro development of three soil-borne nematodes eggs[J]. Strait J Prev Med, 2023, 29(6): 1-3, 36. (in Chinese)
[2] Akelew Y, Whitehead B, Nejsum P. Longevity of Trichuris trichiura infection in the human host[J]. J Travel Med, 2022, 29(7): taac087.
[3] Else KJ, Keiser J, Holland CV, et al. Whipworm and roundworm infections[J]. Nat Rev Dis Primers, 2020, 6(1): 44.
[4] 赵陆源, 黄继磊, 周长海, 等. 2021年全国土源性线虫感染监测结果分析[J]. 中国寄生虫学与寄生虫病杂志, 2024, 42(6): 687-693.
  Zhao LY, Huang JL, Zhou CH, et al. National surveillance on soil-transmitted helminth infections in China, 2021[J]. Chin J Parasitol Parasit Dis, 2024, 42(6): 687-693. (in Chinese)
[5] Ding GD, Zhang YJ. Trichuriasis[J]. N Engl J Med, 2024, 391(16).
[6] Ok KS, Kim YS, Song JH, et al. Trichuris trichiura infection diagnosed by colonoscopy: case reports and review of literature[J]. Korean J Parasitol, 2009, 47(3): 275-280.
[7] 崔静. 胶体染料法与ELISA法对沿江居民感染日本血吸虫情况调查[J]. 齐齐哈尔医学院学报, 2014, 35(12): 1804-1805.
  Cui J. Investigation of Schistosoma japonicum infection among residents along the Yangtze River by colloidal dye method and ELISA[J]. J Qiqihar Univ Med, 2014, 35(12): 1804-1805. (in Chinese)
[8] 黄立中, 吕来福, 黄小妹, 等. 江苏省溧阳市2015—2019年国家血吸虫病监测点疫情监测[J]. 中国热带医学, 2020, 20(7): 634-636.
  Huang LZ, Lyu LF, Huang XM, et al. Epidemic surveillance in national schistosomiasis surveillance sites in Liyang, Jiangsu, 2015-2019[J]. China Trop Med, 2020, 20(7): 634-636. (in Chinese)
[9] 石锋, 杨益, 汪俊云, 等. 快速检测美洲钩虫特异抗体胶体金免疫层析试条方法的建立与效果评价[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(2): 119-123.
  Shi F, Yang Y, Wang JY, et al. Establishment and evaluation of colloid gold-labeled immunochromatographic test strip for rapid detection of antibody against Necator americanus[J]. Chin J Parasitol Parasit Dis, 2018, 36(2): 119-123. (in Chinese)
[10] Roose S, Vande Velde F, Vlaminck J, et al. Serological diagnosis of soil-transmitted helminth (Ascaris, Trichuris and hookworm) infections: a scoping review[J]. PLoS Negl Trop Dis, 2024, 18(4): e0012049.
[11] Katz U, Shoenfeld Y. Pulmonary eosinophilia[J]. Clin Rev Allergy Immunol, 2008, 34(3): 367-371.
[12] Chenery AL, Antignano F, Burrows K, et al. Low-dose intestinal Trichuris muris infection alters the lung immune microenvironment and can suppress allergic airway inflammation[J]. Infect Immun, 2016, 84(2): 491-501.
[13] Dige A, Rasmussen TK, Nejsum P, et al. Mucosal and systemic immune modulation by Trichuris trichiura in a self-infected individual[J]. Parasite Immunol, 2017, 39(1): e12394.
[14] Buonfrate D. Alternative treatment strategies for trichuriasis[J]. Lancet Infect Dis, 2023, 23(3): 266-267.
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