患者，女，39岁，工人，祖籍陕西，出生至今一直在青海格尔木生活、学习、工作。2022年3月1日于中国人民解放军陆军第九五二医院以“胆囊结石”入院治疗。超声检查示胆囊结石（多发），胆囊增大，胆汁淤积；CT示胆囊结石；血常规检查示白细胞总数9.59 × 10⁹/L，中性粒细胞百分比70.8%（升高），嗜酸粒细胞数0.01 × 10⁹/L（下降），嗜酸粒细胞百分比0.1%（下降）；肝功能示丙氨酸转氨酶68.3 U/L（升高），天冬氨酸转氨酶50 U/L（升高），总蛋白59 g/L（下降），白蛋白37.7 g/L（下降）；查体示右侧中上腹压痛。3月2日以腹腔镜行胆囊切除术，胆囊病理切片查见华支睾吸虫虫卵。患者无流行区居住史，仅在青海有喜食生鱼片习惯。结合流行病学史、临床症状和相关辅助检验结果，确诊为华支睾吸虫感染，且为青海首例本地感染病例。3月9日患者痊愈出院，出院后服用吡喹酮（总剂量210 mg/kg，每日3次，连服3 d）治疗。后多次粪检复查未见异常，3个月、两年后回访均未发现异常。

A 39-year-old female worker with her ancestral home in Shaanxi, had lived, studied, and worked in Golmud, Qinghai since birth until now. She was admitted to the Army 952nd Hospital of the People’s Liberation Army of China due to gallbladder stones on March 1, 2022. Ultrasound examinations showed multiple gallbladder stones, an enlarged gallbladder, and bile stasis, and CT scans displayed gallbladder stones. Routine blood tests showed a total white blood cell count of 9.59 × 10⁹/L, a neutrophil percentage of 70.8% (elevated), an eosinophil count of 0.01 × 10⁹/L (decreased), eosinophil percentage of 0.1% (decreased), alanine aminotransferase activity of 68.3 U/L (elevated), aspartate aminotransferase activity of 50 U/L (elevated), total protein of 59 g/L (decreased), and albumin of 37.7 g/L (decreased). Physical examination revealed tenderness in the upper-middle right abdomen. The patient underwent a laparoscopic cholecystectomy on March 2, and the pathological examination of the gallbladder identified Clonorchis sinensis eggs. The patient had no history of living in endemic areas and only had a habit of consuming sliced raw fish in Qinghai. Based on epidemiological history, clinical symptoms, and relevant auxiliary examination results, she was definitively diagnosed with C. sinensis infection, and was the first local case in Qinghai. The patient was cured and discharged from hospital on March 9, and was treated with praziquantel (at a total dose of 210 mg/kg, three times daily for successively 3 days). Subsequent multiple fecal examinations did not show any abnormalities, and no abnormalities were found at 3-month and 2-year follow-up visits.