为了解江西省信丰县人群华支睾吸虫感染现状，将信丰县按地理方位分为东、南、西、北、中5个片区，每个片区选择1个乡（镇）的1个行政村为调查点，每年各调查点整群随机抽取3周岁以上常住居民不少于200人。收集调查者粪样，以改良加藤厚涂片法（一粪二检）检查华支睾吸虫卵并计数，感染者给予吡喹酮治疗（75 mg/kg，分2 d服用），1个月后复查华支睾吸虫虫卵。感染率的比较采用χ²检验。2020—2022年信丰县华支睾吸虫总感染率为6.43%（202/3 142），各年度分别为6.09%（61/1 002）、5.11%（52/1 017）和7.93%（89/1 123）（χ² = 7.30，P < 0.05）。男性华支睾吸虫感染率（8.30%，134/1 614）高于女性（4.45%，68/1 528）（χ² = 19.36，P < 0.01）。40岁及以上年龄组龄人群华支睾吸虫感染率（7.87%，168/2 134）高于40岁以下人群（3.37%，34/1 008）（χ² = 23.04，P < 0.01）。2020年大专及以上人群华支睾吸虫感染率最高（1/8），2021年初中人群感染率最高（6.02%，15/249），2022年文盲人群感染率最高（11.36%，30/264）。感染者共分布于176户，感染1、2和4人的户数分别占87.50%（154/176）、11.36%（20/176）和1.14%（2/176）。经驱虫治疗粪检转阴的感染者197例，其中2例1年后粪检转阳、10例2年后转阳，再感染率为6.09%（12/197）。本调查结果提示，江西省信丰县华支睾吸虫病防控形势依然严峻，部分行政村人群感染率较高，存在家庭多成员感染和再感染情况。

In order to understand the current situation of Clonorchis sinensis infection in Xinfeng County, Jiangxi Province, Xinfeng County was divided into 5 sectors (east, west, south, north and central) according to the geographical location. From each sector, 1 administrative village in 1 township (town) was selected as surveillance site, and no less than 200 permanent residents aged 3 or above were selected by cluster random sampling from each surveillance site in every year. Fecal samples were collected and examined for eggs of C. sinensis by modified Kato-Katz thick smear method (two slides per sample). The infected cases were treated with praziquantel (75 mg/kg) for 2 days, and examined for eggs of C. sinensis one month after treatment. The infection rate was compared by Chi-square test. The total infection rate of C. sinensis was 6.43% (202/3 142) in Xinfeng County from 2020 to 2022, and the annual infection rates were 6.09% (61/1 002), 5.11% (52/1 017) and 7.93% (89/1 123), respectively (χ² = 7.30, P < 0.05). The infection rate of males (8.30%, 134/1 614) was higher than females (4.45%, 68/1 528) (χ² = 19.36, P < 0.01). The infection rates of the elderly groups over 40 years old (7.87%, 168/2 134) was higher than that of the younger age groups (3.37%, 34/1 008) (χ² = 23.04, P < 0.01). The groups with the highest infection rates were college and above in 2020 (1/8), junior high school in 2021 (6.02%, 15/249) and illiteracy in 2022 (11.36%, 30/264), respectively. The infected cases originated from 176 households, and the proportions of households with 1, 2 and 4 infected cases were 87.50% (154/176), 11.36% (20/176) and 1.14% (2/176), respectively. After praziquantel treatment, 197 infected cases achieved negative in fecal test, among them 2 cases turned positive after 1 year and 10 cases turned positive after 2 years. The reinfection rate was 6.09% (12/197). The results indicated that the prevention and control situation for clonorchiasis in Xinfeng County, Jiangxi Province was still severe. The infection rates were relatively high in some administrative villages, with familial clustering of infection and individual reinfection.