目的 分析甘肃省级棘球蚴病定点医院棘球蚴病手术患者的住院费用及其影响因素，为有效控制棘球蚴病医疗费用提供依据。 方法 收集甘肃省级棘球蚴病定点医院2014年1月—2023年12月行外科手术的棘球蚴病患者资料，包括患者基本资料（住院年份、性别、职业、年龄、医保类型、民族）、临床资料（入院途径、是否转科、住院时间、棘球蚴病类型、疾病转归、有无并发症、棘球蚴寄生部位、手术方式）和住院费用资料（住院总费用、手术费用、西药费用、耗材费用、诊断费用、其他费用）。采用SPSS 29.0统计软件进行数据分析，住院费用用中位数表示，单因素分析中非正态分布数据两组间比较使用Mann-Whitney U检验、多组间比较使用Kruskal-Wallis H检验，多因素分析采用多元线性回归方法。 结果 共收集540例棘球蚴病手术患者资料，其中细粒棘球蚴病患者504例，多房棘球蚴病患者36例；女性280例，男性260例。住院总费用合计2 080.98万元，人均住院费用38 528.41元，住院费用中位数为33 732.87元。棘球蚴病患者人均住院费用从2014年的31 276.59元上升至2023年的45 902.34元。男、女住院费用中位数分别为35 232.35、31 891.16元，二者差异有统计学意义（Z = -2.343，P < 0.05）；≥ 61岁患者住院费用中位数最高，为35 233.75元，不同年龄间住院费用差异有统计学意义（P < 0.05）；个体患者住院费用中位数最高，为39 843.04元，不同职业住院费用差异有统计学意义（P < 0.05）；东乡族患者住院费用中位数最高，为65 401.29元，不同民族住院费用差异有统计学意义（P < 0.05）；转入ICU患者住院费用中位数为62 720.04元，高于未转科患者的32 526.89元（Z = -7.440，P < 0.05）；住院时间≥ 21 d患者住院费用中位数最高，为54 433.71元，不同住院时间住院费用差异有统计学意义（P < 0.05）；多房棘球蚴病患者住院费用中位数为43 949.85元，高于细粒棘球蚴病患者的33 555.82元（Z = -3.317，P < 0.05）；转院患者住院费用中位数最高，为104 536.50元，不同类型疾病转归患者住院费用差异有统计学意义（P < 0.05）；有并发症患者住院费用中位数为46 855.89元，高于无并发症患者的32 476.43元（Z = -6.060，P < 0.05）；肝脏棘球蚴病患者住院费用中位数为32 433.02元，低于多脏器棘球蚴病患者的43 550.83元（Z = -4.933，P < 0.05）；行肝移植患者住院费用中位数最高，为170 030.84元，不同手术方式住院费用差异有统计学意义（P < 0.05)。多元线性回归分析结果显示，棘球蚴病手术患者住院费用主要影响因素为年份（t = 5.937，P < 0.01）、年龄（t = 3.349，P < 0.01）、职业（t = 2.238，P < 0.05）、是否转科（t = 8.778，P < 0.01）、住院时间（t = 7.346，P < 0.01）、棘球蚴病类型（t = 6.049，P < 0.01）、有无并发症（t = 5.967，P < 0.01）、棘球蚴寄生部位（t = 3.767，P < 0.01）。 结论 2014—2023年甘肃省级棘球蚴病定点医院棘球蚴病手术患者人均住院费用逐年上升，年份、年龄、职业、是否转科、住院时间、棘球蚴病类型、有无并发症、棘球蚴寄生部位等是影响住院费用的主要因素。

Objective To analyze the hospitalization cost of echinococcosis surgery patients and its influencing factors in Gansu provincial designated echinococcosis hospital, and to provide basis for effieicent management of the medical cost for echinococcosis. Methods Data of echinococcosis patients who underwent surgery at provincial designated hospital in Gansu Province from January 2014 to December 2023 were collected. The data included patients’ basic information (hospitalization year, gender, occupation, age, medical insurance type, ethnicity), clinical information (admission pathway, whether transferred from another department, length of hospital stay, type of echinococcosis, disease outcome, presence of complications, location of cyst, type of surgery), and hospitalization cost data (total hospitalization cost, surgery cost, western medicine cost, consumables cost, diagnostic cost, other costs). Data analysis was conducted using the SPSS 29.0 statistical software. Median was used to represent the hospitalization cost. In single factor analysis, Mann-Whitney U test was used for comparison between two groups, and Kruskal-Wallis H test for comparison among multiple groups for non normal distribution data. Multivariate analysis was performed using multiple linear regression. Results A total of 540 echinococcosis surgery patients’ data were collected, including 504 patients with cystic echinococcosis and 36 patients with alveolar echinococcosis; 280 females and 260 males, with a total combined hospitalization cost of 20 809 800 yuan, a per capita hospitalization cost of 38 528.41 yuan, and median hospitalization cost of 33 732.87 yuan. In 2014 versus 2023, the hospitalization costs for patients with echinococcosis per capita increased from 31 276.59 yuan to 45 902.34 yuan. The median hospitalization costs for male and female cases were 35 232.35 and 31 891.16 yuan, respectively, and the difference was statistically significant (Z = -2.343, P < 0.05); the median hospitalization cost for patients ≥ 61 years old was the highest, 35 233.75 yuan, and the cost difference between different ages was statistically significant (P < 0.05); the median hospitalization cost for individual patients was the highest, 39 843.04 yuan, and the difference in hospitalization costs between different occupations was statistically significant (P < 0.05); the median hospitalization cost for Dongxiang patients was the highest at 65 401.29 yuan, and the difference in hospitalization costs between different ethnic groups was statistically significant (P < 0.05); the median hospitalization cost for patients transferred to ICU was 62 720.04 yuan, higher than the 32 526.89 yuan for patients who were not transferred to the department, and the difference was statistically significant (Z = -7.440, P < 0.05); the median hospitalization cost of patients with hospitalization time ≥ 21 d was the highest at 54 433.71 yuan, and the difference in hospitalization cost between different hospitalization times was statistically significant (P < 0.05); the median hospitalization cost of patients with multilocular echinococcosis was 43 949.85 yuan, higher than that of patients with fine-grained echinococcosis at 33 555.82 yuan (Z = -3.317, P < 0.05); the median hospitalization cost of transferred patients was the highest at 104 536.50 yuan, and the difference in hospitalization costs for different types of disease transfer was statistically significant (P < 0.05); the median hospitalization cost among patients with complications was 46 855.89 yuan, higher than that of 32 476.43 yuan for patients without complications (Z = -6.060, P < 0.05); the median hospitalization cost of patients with hepatic echinococcosis was 32 433.02 yuan, which was lower than that of patients with multi-organ echinococcosis, which was 43 550.83 yuan (Z = -4.933, P < 0.05); the median hospitalization cost of patients who underwent liver transplantation was the highest, which was 170 030.84 yuan, and the difference in hospitalization costs between different surgical procedures was statistically significant (P < 0.05). The results of multivariate linear regression analysis showed that the main factors influencing the cost of hospitalization for patients undergoing surgery for echinococcosis were year of hospitalization (t = 5.937, P < 0.01), age (t = 3.349, P < 0.01), occupation (t = 2.238, P < 0.05), whether or not to transfer to a different department (t = 8.778, P < 0.01), length of hospitalization (t = 7.346, P < 0.01), type of echinococcosis (t = 6.049, P < 0.01), the presence or absence of complications (t = 5.967, P < 0.01), location of cyst (t = 3.767, P < 0.01). Conclusion The per capita hospitalization cost of echinococcosis surgery patients in provincial designated hospital increased year by year from 2014 to 2023, The main factors influencing of hospitalization costs include year, age, occupation, whether or not to transfer to a different department, length of hospitalization, type of echinococcosis, the presence or absence of complications and location of cyst.