收稿日期: 2021-12-21
修回日期: 2022-08-23
网络出版日期: 2022-10-21
An imported case of ovale malaria in Xinjiang during the epidemic period of COVID-19
Received date: 2021-12-21
Revised date: 2022-08-23
Online published: 2022-10-21
新疆和田地区于田县人民医院于2020年12月13日收治1例境外输入疟疾病例。患者自2020年1月至9月有喀麦隆雅温得工作和居住史,曾于3月和5月在当地2次患疟疾,随行医生予抗疟治疗,每次治疗2~3 d后症状好转后停药。9月16日回国,12月13日因高热至39 ℃和上呼吸道症状就诊入院后,进行数次新型冠状病毒核酸检测均为阴性。取患者外周血行疟原虫检测试剂（RDT）为阳性,提示非恶性疟原虫感染;血涂片镜检可见卵形疟原虫环状体,巢式PCR检测结果显示卵形疟原虫阳性,诊断为境外输入卵形疟。予口服双氢青蒿素哌喹片4片/d、磷酸伯氨喹片3片/d,治疗8 d后复查镜检疟原虫阴性。治愈出院后随访3个月,患者无发冷、发热等不适症状。
关键词： 卵形疟; 输入性疟疾; 新型冠状病毒肺炎疫情; 新疆
史光忠 , 张海亭 , 王蒴 , 何海波 , 程侠 , 买买提江·吾买尔 , 于琳 , 阿衣夏木·克尤木 , 赵江山 . 新冠肺炎流行期间新疆报告输入性卵形疟1例[J]. 中国寄生虫学与寄生虫病杂志, 2022 , 40(5) : 689 -691 . DOI: 10.12140/j.issn.1000-7423.2022.05.021
On December 13, 2020, Yutian County People’s hospital reported one imported malaria case in Hotan, Xinjiang. The patient had worked and lived in Yaounde, Cameroon, from January to September 2020. He was infected with malaria twice in March and May 2020. Antimalarial treatment was administrated by the team doctor for 2-3 days in each treatment. The treatment was stopped after the symptoms improved. The patient returned to China on September 16 and was hospitalized on December 13 due to a high fever of 39℃ and upper respiratory symptoms. Multiple detections of COVID-19 nucleic acid showed negative results. Peripheral blood from the patient was taken for Plasmodium rapid diagnostic test (RDT), which showed a positive result suggesting non Plasmodium falciparum infection. Ring stage P. ovale was found in the blood smear. Nested PCR showed positive for P. ovale. A diagnosis of imported ovale malaria was made. The patient was administrated with 4 dihydroartemisinin piperaquine tablets and 3 primaquine phosphate tablets daily. The malaria parasite test became negative after 8 days of treatment. The patient was followed up for 3 months after discharge and had no symptoms of chills or fever.
Key words： Ovale malaria; Imported Malaria; COVID-19 pandemic; Xinjiang
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