为分析2016—2020年漳州市芗城区国家监测点人群土源性线虫感染情况与流行趋势,于2016—2020年选择芗城区天宝镇天宝村、大寨村,浦南镇浦南村、浦林村和石亭镇高坑村为调查点,每年在每个行政村整群抽取3周岁以上的常住人口200人,采用改良加藤厚涂片法（Kato-Katz法）（一粪两检）镜检土源性线虫卵,3~9周岁儿童用透明胶纸肛拭法检查蛲虫卵。对钩虫阳性者采用试管滤纸培养法进行钩蚴培养并鉴定虫种。每个行政村随机抽取5户,每户采集1份田地或菜园土样,检查钩蚴和蛔虫卵。2016—2020年共调查5 309人,总感染率为3.0%（159/5 309）,其中,钩虫、鞭虫的感染率分别为2.9%（154/5 309）、0.1%（5/5 309）,未发现蛔虫感染者;共检查3~9岁儿童625人,蛲虫感染率为27.8%（174/625）。男、女性感染率分别为3.7%（96/2 608）、2.3%（63/2 701）,二者差异有统计学意义（χ² = 8.31,P < 0.01）。≥ 65岁年龄人群的感染率最高,为7.3%（79/1 077）,各年龄组感染率差异有统计学意义（χ² = 123.51,P < 0.01）。职业分布中农民的感染率最高,为3.6%（157/4 325）,不同职业人群感染率差异有统计学意义（χ² = 32.95,P < 0.01）。文盲半文盲人群的感染率最高,为10.1%（79/781）,不同文化程度人群感染率差异有统计学意义（χ² = 171.18,P < 0.01）。2016—2020年,土源性线虫总感染率分别为3.9%（44/1 126）、1.0%（11/1 104）、7.6%（78/1 029）、0.9%（9/1 013）和1.6%（17/1 037）,儿童蛲虫感染率分别为34.0%（33/97）、28.4%（27/95）、30.9%（30/97）、30.9%（46/149）和20.3%（38/187）,钩虫感染率分别为3.6%（41/1 126）、1.0%（11/1 104）、7.4%（76/1 029）、0.9%（9/1 013）和1.6%（17/1 037）,总感染率和钩虫感染率不同年度间的差异有统计学意义（χ² = 114.90、110.32,P < 0.01）;仅2016、2018年发现有鞭虫感染,感染率分别为0.3%（3/1 126）和0.2%（2/1 029）。钩虫感染程度以轻度感染为主,占98.1%（151/154）;鞭虫均为轻度感染（5/5）。2016—2020年共采集土样115份,钩蚴阳性率为8.7%（10/115）,未检出人蛔虫卵,阳性土壤均来自菜园,钩蚴经鉴定均为美洲钩蚴。提示2016—2020年芗城区农村人群土源性线虫感染率呈明显下降趋势,儿童蛲虫感染仍维持较高水平,应继续加强监测与防治工作。

To analyze the prevalence and epidemic trend of soil-transmitted nematode infection at a national surveillance site of Xiangcheng District in Zhangzhou City from 2016 to 2020. Tianbao Village and Dazhai Village in Tianbao Town, Punan Village and Pulin Village in Punan Town, and Gaokeng Village in Shiting Town were selected as the survey sites in Xiangcheng District. No less than 200 permanent residents aged 3-years or above were selected from each administrative village. Fecal samples were collected from the residents recruited in the study and were examined for soil-transmitted nematode eggs (two slide-reading per sample) using the modified Kato-Katz thick smear method. The cellophane tape method was used to detect the eggs of Enterobius vermicularis in children aged 3-9 years. For individuals with hookworm infection, the test-tube filter paper incubation method was used to culture hookworms and identify the species of hookworms. Five households were randomly selected from each village, and one soil sample from the field or vegetable garden was collected for each household to check for Ascaris eggs and hookworms. From 2016 to 2020, a total of 5 309 local residents were tested, and the total infection rate was 3.0% (159/5 309). The infection rates of hookworm and Trichuris trichiura were 2.9% (154/5 309) and 0.1% (5/5 309), respectively. No A. lumbricoides infection was found. Six hundred twenty-five children aged 3-9 were examined, and the E. vermicularis infection rate was 27.8% (174/625). The infection rates for males and females were 3.7% (96/2 608) and 2.3% (63/2 701), respectively. The difference was statistically significant (χ² = 8.31, P < 0.01). The highest infection rate was 7.3% (79/1 077) in ≥ 65 years age group with a statistically significant difference between the age groups (χ² = 123.51, P < 0.01). The infection rate was higher among farmers, with 3.6% (157/4 325) than in other occupations. The difference was statistically significant (χ² = 32.95, P < 0.01). The highest infection rate was in illiterate and semi-literate residents 10.1% (79/781) with statistically significant difference between the educational levels (χ² = 171.18, P < 0.01). The total infection rates of soil-derived nematodes between 2016 and 2020 were 3.9% （44/1 126）, 1.0% （11/1 104）, 7.6% （78/1 029）, 0.9% （9/1 013） and 1.6% （17/1 037）, respectively. The infection rates of E. vermicularis in children were 34.0% (33/97), 28.4% (27/95), 30.9% (30/97), 30.9% (46/149) and 20.3% (38/187), respectively. The infection rates of hookworm were 3.6% (41/1 126), 1.0% (11/1 104), 7.4% (76/1 029), 0.9% (9/1 013) and 1.6% (17/1 037), respectively. There were significant differences in the total infection rate and hookworm infection rate among different years (χ² = 114.90, 110.32; P < 0.01). T. trichiura infections were only found in 2016 and 2018. The infection rates were 0.3% (3/1 126) and 0.2% (2/1 029), respectively. The majority of the hookworm infected cases had a mild infection, accounting for 98.1% (151/154). All T. trichiura infected cases were mild infections (5/5). From 2016 to 2020, a total of 115 soil samples were collected. The positive rate of hookworm larvae was 8.7% (10/115), and all were identified to be Necator americanus. No human Ascaris eggs were detected. The positive soils were all from vegetable gardens. From 2016 to 2019, the infection rate of soil-transmitted nematodes in the rural population in Xiangcheng District showed a significant decrease. The E. vermicularis infection in children still remains at high level, and monitoring and prevention should continue to be strengthened.