收稿日期: 2020-09-06
修回日期: 2020-11-17
网络出版日期: 2021-05-28
基金资助
国家自然科学基金(81802028);新乡医学院博士科研启动基金(XYBSKZZ201631);新乡市科技攻关计划项目(GG2019034)
Affect of Trichomonas vaginalis infection on male reproductive system and its mechanisms
Received date: 2020-09-06
Revised date: 2020-11-17
Online published: 2021-05-28
Supported by
National Natural Science Foundation of China(81802028);Doctoral Research Fund of Xinxiang Medical University(XYBSKZZ201631);Science and Technology Project of Xinxiang Province(GG2019034)
段玉娟 , 李朋举 , 桑雨慧 , 吴璞成 , 商雨佳 , 郝利霞 , 王帅 , 李祥瑞 , 张振超 . 阴道毛滴虫感染对男性生殖系统的影响及其机制[J]. 中国寄生虫学与寄生虫病杂志, 2021 , 39(4) : 532 -536 . DOI: 10.12140/j.issn.1000-7423.2021.04.018
Trichomonas vaginalis is a type of flagellated protozoan and the most common sexually transmitted pathogens in the world. T. vaginalis mainly parasitizes in the female vagina, leading to trichomonal vaginitis. In addition, T. vaginalis can also infect males, and the parasites may retrograde to the bladder, prostate, seminal vesicle, testis, epididymis and other tissues, through the urogenital tract, thus causing serious damage to sperm cells or other tissues; causing urethritis, prostatitis, prostate cancer, asthenospermia or azoospermia, eventually affecting the male fertility. However, T. vaginalis infection in males often presents mild or no clinical symptoms, resulting in ignorance of the infection. In this paper, we review the related mechanisms underlying the T. vaginalis infection-induced abnormal sperm, testicular and prostate functions, and thereby male infertility.
Key words： Trichomonas vaginalis; Infertility; Sperm; Prostate; Testicles
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