收稿日期: 2021-06-21
修回日期: 2021-07-08
网络出版日期: 2021-08-12
基金资助
国家社会科学基金重大项目(16ZDA237)
New progress in basic and clinical research of advanced schistosomiasis
Received date: 2021-06-21
Revised date: 2021-07-08
Online published: 2021-08-12
Supported by
Major Projects of National Social Science Foundation of China(16ZDA237)
刘蓉 , 闻礼永 . 晚期血吸虫病基础和临床研究新进展[J]. 中国寄生虫学与寄生虫病杂志, 2021 , 39(4) : 429 -436 . DOI: 10.12140/j.issn.1000-7423.2021.04.002
At present, the endemic situation of schistosomiasis is at the lowest level in history in China, and the infection rate has decreased significantly, but there are still a large number of patients with advanced schistosomiasis. Advanced schistosomiasis is the most serious type of schistosomiasis, which seriously endangers the health and quality of life of patients. Liver granuloma and fibrosis caused by Schistosoma eggs are the leading cause for the death of advanced schistosomiasis patients. This article summarizes the pathological mechanism, determine approaches, treatment and prognosis of liver fibrosis in basic and clinical research of advanced schistosomiasis, hoping to provide reference information for future schistosomiasis prevention and treatment.
Key words： Schistosomiasis; Advanced; Hepatic fibrosis; Basic; Clinical
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