收稿日期: 2020-06-24
修回日期: 2020-09-14
网络出版日期: 2021-04-30
Current status of Ascaris lumbricoides infection in populations in Yunan Province, 2015
Received date: 2020-06-24
Revised date: 2020-09-14
Online published: 2021-04-30
为了解云南省人群蛔虫感染现状,于2015年按照《全国人体重点寄生虫病现状调查方案》和实施细则要求,采用分层整群随机抽样的方法从全省抽取10个县(市)共20个调查点,每个调查点不少于250人,调查对象为1岁及以上本地常住人口,收集受检者粪样,采用改良加藤厚涂片法镜检虫卵(一粪二检)。共粪检5 067份样品,蛔虫感染阳性381份,感染检出率为7.5%。其中未受精蛔虫卵、受精蛔虫卵和混合感染者分别占42.5%(162/381)、39.4%(150/381)、18.1%(69/381)。感染度为轻、中和重度的分别占68.0%(259/381)、29.1%(111/381)、2.9%(11/381)。生态区分布以藏东-川西生态区最高(16.6%,211/1 271),其中贡山县感染检出率最高(26.2%,200/762),10个县(市)均发现感染者,不同生态区以及各县之间感染检出率差异均有统计学意义(P < 0.01)。女性感染检出率(8.2%,218/2 645)高于男性(6.7%,163/2 422)(P > 0.05)。各年龄组均有感染者,其中小于10岁组的感染检出率最高(18.1%,119/657)(P < 0.01)。民族以独龙族感染检出率最高(48.9%,131/268)(P < 0.01)。教师感染检出率为(2/6),学龄前儿童感染检出率为(21.4%,93/435)。文化程度以文盲感染检出率最高(13.1%,177/1 347)(P < 0.01)。不同年龄组、民族、职业之间感染检出率之间差异均有统计学意义(P < 0.01)。云南省蛔虫感染存在区域差异,局部地区感染检出率和感染度偏高。
字金荣 , 汪丽波 , 杨亚明 , 李奔福 , 严信留 , 彭佳 , 蔡璇 , 王正青 , 杜尊伟 , 吴方伟 . 2015年云南省人群蛔虫感染现状调查[J]. 中国寄生虫学与寄生虫病杂志, 2021 , 39(2) : 273 -277 . DOI: 10.12140/j.issn.1000-7423.2021.02.024
To understand and analyze the infection status of Ascaris lumbricoides in Yunnan Province, a cross-sectional survey was conducted according to the National Survey Program and Implementation Details of Key Parasitic Diseases in 2015. Twenty sites of 10 counties (cities) were selected using the stratified cluster sampling method and stool samples were collected from no less than 250 permanent residents (≥ 1 year old) per site for microscopical examination using modified Kato-Katz thick smear method (two-reading/sample). A total of 5 067 participants were enrolled and 381 of them were infected with A. lumbricoides, with an overall prevalence of 7.5%. Among the 381 residents, the proportions of infection with unfertilized Ascaris eggs, fertilized Ascaris eggs and a mixture of both were 42.5%, 39.4% and 18.1%, respectively. The proportions of mild, moderate and heavy infections were 68.0%, 29.1% and 2.9%, respectively. Different detection rates were observed among different ecological regions, i.e., the eastern Tibet-western Sichuan region had the highest detection rate (16.6%, 211/1 271), in which the Gongshan County had the highest rate (26.2%, 200/762), and Ascaris infection was detected in all 10 counties of this region. There was a statistically significant difference in the detection rate among different ecological regions and counties (P < 0.01). The detection rate in females (8.2%, 218/2 645) was higher than that in males (6.7%, 163/2 422) (P > 0.05). All age groups were found with Ascaris infection, but the highest detection rate was found in children under 10 years (18.1%, 119/657) (P < 0.01). The Dulong ethnicity had the highest detection rate (48.9%, 131/268) among ethnic groups (P < 0.01). Teachers had an detection rate of (2/6), while the pre-school children had an infection rate of 21.4% (93/435). Among the examinees with different educational levels, the illiterate had the highest detection rate (13.1%, 177/1347) (P < 0.01). The detection rate of Ascaris lumbricoides in Yunnan Province showed significant differences with regard to age, ethnicity, occupation, and educational level (P < 0.01). Overall, the detection rate showed a differential distribution among regions, with particularly high rate and infection intensity in some areas.
Key words: Yunnan Province; Ascaris lumbricoides; detection rate; Survey
| [1] | Wang LB, Wu FW, Du ZW, et al. Prevalence of infection with soil-transmitted nematodes in Yunnan Province[J]. J Pathogen Biol, 2015,10(7):634-637, 658. (in Chinese) |
| [1] | ( 汪丽波, 吴方伟, 杜尊伟, 等. 云南省人群土源性线虫感染现状调查[J]. 中国病原生物学杂志, 2015,10(7):634-637, 658.) |
| [2] | Dong Y, Du ZW, Zhang ZX, et al. Analysls on the epidemic status of intestinal parasitic diseases in Yunnan Province[J]. Chin J Parasit Dis Control, 2005,18(6):448-450. (in Chinese) |
| [2] | ( 董莹, 杜尊伟, 张再兴, 等. 云南省肠道寄生虫病现状分析[J]. 中国寄生虫病防治杂志, 2005,18(6):448-450.) |
| [3] | Chinese Center for Disease Control and Prevention National Institute of Parasitic Diseases. Report on the national survey of important human parasitic diseases in China (2015)[M]. Beijing: People’s Medical Publishing House, 2018: 54-64. (in Chinese) |
| [3] | ( 中国疾病预防控制中心寄生虫病预防控制所. 2015年全国人体重点寄生虫病现状调查报告[M]. 北京: 人民卫生出版社, 2018: 54-64.) |
| [4] | General Office of the National Heath and Family Planning Commission. Notice of the general office of the national heath and family planning commission on the investigation plan on the status of key human parasitic diseases[J]. Cap J Pub Heal, 2014,8(6):241-244. (in Chinese) |
| [4] | ( 国家卫生计生委办公厅. 国家卫生计生委办公厅关于印发全国人体重点寄生虫病现状调查方案的通知[J]. 首都公共卫生, 2014,8(6):241-244.) |
| [5] | Chen YD, Huang JL, Zhu HH, et al. China’s control process of soil-transmitted helminth infections from pandemic to low-endemic levels[J]. Chin J Parasitol Parasit Dis, 2019,37(4):395-398. (in Chinese) |
| [5] | ( 陈颖丹, 黄继磊, 朱慧慧, 等. 我国土源性线虫高感染到低感染水平的防治历程[J]. 中国寄生虫学与寄生虫病杂志, 2019,37(4):395-398.) |
| [6] | Zhu TJ, Chen YD, Xu LQ. Prevention and treatment of Ascariasis in demonstration plots of integrated control from 2006 to 2009[J]. Chin J Schisto Control, 2011,23(5):490-494. (in Chinese) |
| [6] | ( 诸廷俊, 陈颖丹, 许隆祺. 我国寄生虫病综合防治示范区蛔虫病3年防治效果[J]. 中国血吸虫病防治杂志, 2011,23(5):490-494.) |
| [7] | Du ZW, Jiang JY, Li HB, et al. Investigation of prevalence of soil-transmitted nematode infections among Lahu Ethnic residents in Xiaojie Township, Jinghong City, Yunnan Province[J]. Chin J Schisto Control, 2014,26(1):75-77. (in Chinese) |
| [7] | ( 杜尊伟, 姜进勇, 李鸿斌, 等. 景洪市小街乡拉祜族居民土源性线虫感染调查[J]. 中国血吸虫病防治杂志, 2014,26(1):75-77.) |
| [8] | Zhu AY, Du K, Li AM, et al. Surveillance results of national monitoring site for soil-transmitted nematode infections in Guizhou Province in 2011—2015[J]. Chin J Parasitol Parasit Dis, 2017,35(5):445-449, 455. (in Chinese) |
| [8] | ( 朱爱娅, 杜坤, 李安梅, 等. 2011—2015年贵州省土源性线虫感染监测结果分析[J]. 中国寄生虫学与寄生虫病杂志, 2017,35(5):445-449, 455.) |
| [9] | Wu XL, Duan HJ, Fu YR, et al. Prevalence of Ascaris infection and the contamination of soil with Ascaris eggs in the rural areas of Ningxia during 2015—2016[J]. Chin J Parasitol Parasit Dis, 2019,37(2):173-177. (in Chinese) |
| [9] | ( 吴向林, 段红菊, 付益仁, 等. 2015—2016年宁夏农村地区人群蛔虫感染及土壤蛔虫卵污染情况调查[J]. 中国寄生虫学与寄生虫病杂志, 2019,37(2):173-177.) |
| [10] | Zeng XJ, Jiang WS, Xie SY, et al. Trends of soil-transmitted nematodiasis infections in Jiangxi Province[J]. Chin J Schisto Control, 2017,29(6):710-715. (in Chinese) |
| [10] | ( 曾小军, 姜唯声, 谢曙英, 等. 江西省土源性线虫病流行趋势分析[J]. 中国血吸虫病防治杂志, 2017,29(6):710-715.) |
| [11] | Zhu TJ, Zhou CH, Wang JJ, et al. Evaluation of soil-transmitted Nematodiasis control after cessation of intervention measures in eight demonstration plots[J]. Chin J Parasitol Parasit Dis, 2017,35(5):439-444. (in Chinese) |
| [11] | ( 诸廷俊, 周长海, 王聚君, 等. 8个干预示范区停止干预措施后土源性线虫病的控制现状评价[J]. 中国寄生虫学与寄生虫病杂志, 2017,35(5):439-444.) |
| [12] | Keiser J, Utzinger J. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis[J]. JAMA, 2008,299(16):1937-1948. |
| [13] | Li ZJ, Lan WM, Ge J, et al. Endemic status of human Ascaris lumbricoides infection in Jiangxi Province[J]. Chin J Parasitol Parasit Dis, 2019,37(1):36-40. (in Chinese) |
| [13] | ( 李召军, 兰炜明, 葛军, 等. 江西省人体蛔虫感染现状分析[J]. 中国寄生虫学与寄生虫病杂志, 2019,37(1):36-40.) |
| [14] | Li BF, Wu FW, Yan XL, et al. Survey of key human parasitic infections in the Eastern Tibet and Western Sichuan Eco-region, Yunnan Province, China[J]. Chin J Parasitol Parasit Dis, 2019,37(6):718-722. (in Chinese) |
| [14] | ( 李奔福, 吴方伟, 严信留, 等. 云南省藏东-川西生态区人体重点寄生虫病流行现状调查[J]. 中国寄生虫学与寄生虫病杂志, 2019,37(6):718-722.) |
| [15] | Chen YD, Zhu HH, Huang JL, et al. Status and working principals of soil-transmitted nematodiasis during new period in China[J]. Chin J Schisto Control, 2019,31(1):23-25. (in Chinese) |
| [15] | ( 陈颖丹, 朱慧慧, 黄继磊, 等. 我国土源性线虫病流行现状及新时期防控原则[J]. 中国血吸虫病防治杂志, 2019,31(1):23-25.) |
| [16] | Cai MJ, He YJ, Meng C, et al. Investigation and epidemiological analysis of intestinal parasite infection among pupils in a minority area of Yunnan Province[J]. Lab Med and Clin Med, 2016,13(16):2292-2293, 2296. (in Chinese) |
| [16] | ( 蔡敏佳, 何宇佳, 孟铖, 等. 云南省某少数民族地区小学生肠道寄生虫感染调查及流行病学分析[J]. 检验医学与临床, 2016,13(16):2292-2293, 2296.) |
| [17] | Chen YD, Zhou CH, Zhu HH, et al. National survey on the current status of important human parasitic diseases in China in 2015[J]. Chin J Parasitol Parasit Dis, 2020,38(1):5-16. (in Chinese) |
| [17] | ( 陈颖丹, 周长海, 朱慧慧, 等. 2015年全国人体重点寄生虫病现状调查分析[J]. 中国寄生虫学与寄生虫病杂志, 2020,38(1):5-16.) |
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