目的 了解棘球蚴病防治项目实施对四川省棘球蚴病患者治疗费用的影响,为制定棘球蚴病救助政策提供参考。 方法 收集2016—2020年四川省4所三甲医院棘球蚴病外科治疗病例的资料,包括患者的基本信息、病灶分型、住院天数、手术费用、医保补助、国家项目补助等资料信息。采用SPSS 18.0统计学软件进行统计分析。 结果 收集的504例病例资料中,男女性别比为1 ∶ 1.2,细粒棘球蚴病（114例）和多房棘球蚴病（175例）分型比为1 ∶ 1.5,平均年龄（38.6 ± 14.5）岁。手术部位以肝脏为主90%（414/460）。手术方式以肝部分切除为主24.7%（90/365）,合并其他手术的病例82例,肝移植病例33例。住院时间天数中位数为15 d。2016年与2020年相比中位数住院总费用由41 234元上升为66 356元,呈逐年上升趋势（P < 0.01）。不同医院、年度、手术年龄、住院时间、棘球蚴病分型及手术方式对住院总费用有影响(P < 0.05)。补助数据完整的237例患者中,住院费用总额为16 833 040元,住院费用中位数为51 172元,国家棘球蚴病项目补助金总额为4 645 709元,中位数22 000元,补助 > 20 000元者占51.9%;医疗保险和棘球蚴病项目救助后,需自付医疗费用的病例192例,合计金额2 710 793元,中位数5 888元,自付0~5 000者最多（58.2%）,其中47人零支付。 结论 国家棘球蚴病救治项目很大程度上减轻了患者的医疗费用负担。

Objective To evaluate the impact of the echinococcosis prevention and treatment project on the treatment cost for echinococcosis patients in Sichuan Province, in order to provide a scientific basis for the formulation of subsidy policy. Methods Data of surgical treatment of echinococcosis patients in four 3A grade hospitals in Sichuan Province from 2016 to 2020 were collected, including the basic information, lesion type, hospitalization days and expenses, medical insurance subsidies, state project subsidies, etc. SPSS 18.0 statistical software was used for statistical analysis. Results A total of 504 cases were collected, with a male-to-female ratio of 1 ∶ 1.2. The ratio of cystic echinococcosis granulose(114 cases) to alveolar echinococcosis (175 cases) was 1 ∶ 1.5, and the average age was (38.6 ± 14.5) years. The main surgical site was in liver (90%, 414/460). The major operative strategy was partial hepatectomy (24.7%, 90/365). Eighty-two cases received combined surgery and 33 cases received liver transplantation. The median length of hospitalization was 15 days. From 2016 to 2020, the median of total cost of hospitalization showed a trend of yearly increase. Significant factors that influence the hospitalization expense included different hospitals, year of admission, the age upon operation, length stay in hospital, type of echinococcosis and operation method (P < 0.05). Of the 237 patients with complete subsidy data, the total cost of hospitalization was 16 833 040 yuan, with a median cost of 51 172 yuan. The total amount of the national echinococcosis subsidy project was 4 645 709 yuan, with a median of 22 000 yuan. Most of the patients received a subsidy of > 20 000 yuan (51.9%). After compensated by medical insurance and echinococcosis subsidy, 192 patients need to pay for their own cost. The total amount of self-payment was 2 710 793 yuan, with a median of 5 888 yuan. Most of the patients paid 0-5000 yuan (58.2%), with 47 patients paying no cost. Conclusion The government echinococcosis subsidy program has greatly reduced the burden of patients for medical cost.