为了解云南省人体钩虫病流行现状,于2015年按照《全国人体重点寄生虫病现状调查方案》和实施细则要求,采用分层整群随机抽样方法从全省抽取10个县（市）共20个调查点,每个调查点不少于250人,调查对象为1岁及以上本地常住人口,收集受检者粪样,采用改良加藤厚涂片法检测钩虫卵,试管滤纸培养法鉴别钩虫虫种。共调查5 067人,钩虫感染率为9.0%（457/5 067）,其中轻、中、重度感染者分别占94.5%（432/457）、2.8%（13/457）和2.6%（12/457）。对160例钩虫感染者进行钩虫虫种鉴别,其中感染美洲钩虫139例,感染十二指肠钩虫16例,混合感染5例。男性和女性钩虫感染率分别为8.4%（204/2 422）、9.6%（253/2 645）,60岁及以上年龄组感染率最高（12.9%）,民族以独龙族的感染率最高（39.6%）,职业以农民感染率最高（9.4%）,文化程度以小学人群感染率最高（9.5%）。滇桂粤南部生态区感染率最高（17.1%）,其中河口县人体钩虫感染率高达30.6%。高、中、低经济水平地区感染率分别为0.8%（6/759）、13.6%（311/2 287）和6.9%(140/2 021）,差异有统计学意义（P < 0.01）。云南省部分地区人体钩虫感染率仍然较高,应继续加强对农民、老年人和直过少数民族等重点人群的防治工作。

To understand the prevalence of human hookworm infection in Yunnan Province, a total of 20 survey sites in 10 counties (cities) in Yunnan Province were selected by the stratified cluster random sampling method in 2015, according to the National Survey Plan for the Status of Key Human Parasitic Diseases and the implementation guideline. In each site, no less than 250 permanent residents aged 1 year and above were surveyed. Fecal samples were collected from the participants for examining, hookworm eggs using modified Kato-Katz method. The hookworm species was identified by the in vitro filter culture method. A total of 5 067 residents were examined, with an infection rate of 9.0% (457/5 067), among them, 94.5% (432/457) were severe, 2.8% (13/457) moderate and 2.6% (12/457) mild infection. Species identification was performed for 160 cases, of them, 139 was infected with Ancylostoma americanum, 16 with A. duodenale, while 5 with mixed infection. The infection rate was 8.4% (204/2 422) in males and 9.6% (253/2 645) in females. Highest infection rate was detected in the age group of 60 years and above (12.93%), in Dulong ethnic group (39.55%), in farmers (9.4%), and in the group of education level of primary school level (9.5%). The human hookworm infection rate was highest in the ecological area of southern part of Yunnan, Guangxi and Guangdong (17.14%), with Hekou County in particular having infection rate up to 30.6%. Human hookworm infection rate was 0.8% (6/759), 13.6% (311/2 287) and 6.9% (140/2 021) in regions with high, medium and low economic levels, respectively, with significant differences between the regions(P < 0.01). In conclusion, the human hookworm infection rate remains high in part of Yunnan Province, efforts should be made to continuously strengthen prevention and control measures in farmers, elders, and strait through ethnic minorities.