为调查贵州省都匀地区孕产妇弓形虫感染情况,收集2015-2018年就诊于贵州省都匀地区黔南州人民医院进行孕期、产前检查的妇女及曾出现过流产、死胎、畸形等病理妊娠的孕产妇血清,进行弓形虫特异性抗体IgM及IgG的ELISA检测。应用SPSS 17.0软件进行统计学分析,弓形虫抗体阳性率采用χ ²检验进行比较。共征集6 931例孕产妇,包括6 825例正常孕产妇和106例病理妊娠孕产妇。年龄为18~45岁,以汉族、布依族、苗族等为主。孕产妇弓形虫总抗体阳性率为6.1%（424/6 931）,其中正常孕产妇弓形虫抗体阳性率为5.9%（403/6 825）,病理妊娠孕产妇弓形虫抗体阳性率为19.8%（21/106）,差异有统计学意义（P < 0.01）。汉族、布依族、苗族、水族、土家族、侗族的孕产妇弓形虫抗体阳性率分别为7.5%（215/2 886）、5.4%（132/2 453）、5.5%（71/1 300）、2.3%（3/131）、2.0%（2/100）、1.6%（1/61）,差异有统计学意义（P < 0.05）。职业为干部、教师、农村劳作、其他的孕产妇弓形虫抗体阳性率分别为1.3%（22/1 714）、1.8%（22/1 216）、13.2%（320/2 418）、3.8%（60/1 583）,差异有统计学意义（P < 0.01）。有、无动物接触史的孕产妇弓形虫抗体阳性率分别为26.2%（361/1 379）和1.1%（63/5 552）,差异有统计学意义（P < 0.01）。提示贵州省都匀地区孕产妇弓形虫抗体阳性者以有病理妊娠反应、汉族、主要从事农村劳作、有动物接触史等为主。

To investigate the status of Toxoplasma infection in pregnant and postpartum women in Duyun district of Guizhou Province, China, serum samples were collected during 2015-2018 from pregnant and postpartum women receiving regular checkups and the women who had pathological pregnancies such as miscarriage, stillbirth, and deformity in Qiannan People′s Hospital, to test for specific IgM and IgG antibodies against Toxoplasma by ELISA. SPSS 17.0 software was used for statistical analysis. The positive rates of serum Toxoplasma antibody were compared by chi-square test. A total of 6 931 pregnant and postpartum women participated in the survey, including 6 825 normal pregnancies and parturients, and 106 pathological pregnancies and parturients. The age of the participants ranged 18-45 years, with ethnicities mainly of Han, Buyi, and Miao. The overall positive rate of Toxoplasma antibody was 6.1%(424/6 931), composed of 5.9%(403/6 825) in normal pregnant and postpartum women, and 19.8% (21/106) in pathological pregnancies and parturients (P < 0.01). There was a significant difference in the positive rate of Toxoplasma antibody among Han (7.5%, 215/2 886), Miao (5.4%, 132/2 453), Buyi (5.5%, 71/1 300), Shui (2.3%, 3/131), Tujia (2.0%, 2/100) and Dong (1.6%, 1/61) ethnicities (P < 0.05). There was also a significant difference in the positive rate of Toxoplasma antibody among cadres (1.3%, 22/1 714), teachers (1.8%, 22/1 216), rural workers (13.2%, 320/2 418) and other occupations (3.8%, 60/1 583) (P < 0.01). It was noted that the pregnant women with and without history of contacting with animals was 26.2% (361/1 379) and 1.1% (63/552), respectively, with the difference being statistically significant(P < 0.01). The results demonstrate the pregnant women with positive Toxoplasma antibody in Duyun District of Guizhou Province are mainly those having pathological pregnancyies, being Han ethnicity, engaging in rural farming work, and having contacts with animals.