中国寄生虫学与寄生虫病杂志 ›› 1984, Vol. 2 ›› Issue (4): 234-237.

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我国保有的食蟹猴疟原虫的生物学特征及株型的探讨

王兴相,胡友梅,邓保忠   

  1. 第三军医大学寄生虫学教研室; 第三军医大学药理学教研室; 第三军医大学寄生虫学教研室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1984-11-30 发布日期:2017-01-12

STUDIES ON THE BIOLOGICAL CHARACTERISTICS AND THE STRAIN-TYPE OF PLASMODIVM CYNOMOLGIMAI NTAINED IN CHINA

  • Received:2017-01-12 Revised:2017-01-12 Online:1984-11-30 Published:2017-01-12

摘要: 本虫株具有下列特征。红外期:形态不规则,第7天胞质内出现液泡、分叶,第8天成熟,同一天末即可在外周血内找到原虫。复发率为62.5%。红内期:喜入侵晚期网织红细胞(Ⅳ期),血传感染持续期可长达7年以上。孢子增殖期:在大劣按蚊、斯氏按蚊及雷氏按蚊体内都能完成孢子增殖:在雷氏按蚊体内发育不良,胃壁上黑孢子形成率可高达42.3%;在大劣按蚊体内,卵囊圆形或椭圆,其最大径未超过60μm者:子孢子最早可于7.5天进腺。根据上述特点,与该疟原虫的各株进行比较,初步认为本虫株可能属于柬埔寨株。

关键词: 生物学特征, 食蟹猴疟原虫, 大劣按蚊, 感染率, 网织红细胞, 雷氏按蚊, 潜隐体, 斯氏按蚊, 恒河猴, 株型

Abstract: Exoerythrocytic stage: On the 7th day after sporozoite inoculation, intact crypto-zoites generally appear irregularly in outline; some of them may be lobed and some may contain 1-4 vacuoles 4-6μm in diameter; their peripheral nuclei arrange at random, maturing at the 8th day. Parasitemia may appear by the end of the 8th day. The relapse rate of this parasite in Macaca mulatta is about 62.5%.Blood stage: The parasites prefer to invade the 4th stage reticulocytes. Trophozoite--induced infections could be maintained for over 7 years.Sporogony: It takes place in Anopheles dims, A. stephensi and A. lesteri, the first two species being more susceptible than the last one. Oocysts are round or elliptical in shape, they measure 35±5.2μm in diameter at the 8th day and 60μm at the maxi-mum; sporozoites can be found in the salivary glands at the 8th day.Based on the findings mentioned above, this malaria parasite may be considered as the Cambodian strain of Plasmodium cynomolgi.