CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2021, Vol. 39 ›› Issue (1): 112-119.doi: 10.12140/j.issn.1000-7423.2021.01.017

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Research progress on immune regulation of medical protozoa-related proteins

LIU Bing(), WANG Qi, HE Yong-jun, HE Ping*()   

  1. Medical Department of Xizang Minzu University, Xianyang 712082, China
  • Received:2020-08-03 Revised:2020-11-28 Online:2021-02-28 Published:2021-03-10
  • Contact: HE Ping E-mail:imsunnylb@163.com;hepingyixue@126.com
  • Supported by:
    National Natural Science Foundation of China(81860365);Natural Science Foundation of Tibet Autonomous Region([XZ2018ZRG-80(Z)]);Natural Science Foundation of Tibet Autonomous Region(18MDZ02)

Abstract:

Protozoan, a type of single-celled eukaryotes with simple structure, is widely distributed in natural world. Medical protozoa can parasitize humans in body fluid, tissues and cells, and regulate host immune response, escaping from attack of the host immune system, and enabling survival and proliferation in the host and causing the occurrence of disease. In this paper, we summarize the immunomodulatory effects of proteins associated with Plasmodium, Toxoplasma gondii, Leishmania donovani and Giardia lamblia, in order to provide information for the prevention and treatment of medical protozoa-related parasitic diseases.

Key words: Protozoan, Protein, Immune regulation

CLC Number: