CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2020, Vol. 38 ›› Issue (3): 378-382.doi: 10.12140/j.issn.1000-7423.2020.03.019
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SUN Cheng-song1,2, HU Wei1,*(), WANG Tian-ping2
Received:
2019-10-21
Online:
2020-06-30
Published:
2020-07-07
Contact:
Wei HU
E-mail:huw@fudan.edu.cn
Supported by:
CLC Number:
SUN Cheng-song, HU Wei, WANG Tian-ping. Advances in research on schistosome-host interactions mediated by extracellular vesicles[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(3): 378-382.
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URL: https://www.jsczz.cn/EN/10.12140/j.issn.1000-7423.2020.03.019
EVs类型 | 外泌体 | 微囊泡 | 凋亡小体 |
---|---|---|---|
尺寸 | 30~100 nm | 100~1 000 nm | 1~5 μm |
形态 | 杯状 | 形态多样 | 形态多样 |
离心力 | 100 000~200 000 g | 10 000~20 000 g | < 10 000 g |
蛋白标志物 | CD63、 CD9、 CD81、肿瘤特异性糖蛋白(tumor-specific glycoprotein 101,Tsg101)、 ALG-2相互作用蛋白X(ALG-2-interacting protein X,Alix) | 蛋白质、 非编码 RNA、 mRNA | 组蛋白 |
主要组分 | 蛋白质、 非编码 RNA、 mRNA | 蛋白质、非编码RNA、 mRNA | 蛋白质、 非编码RNA、 mRNA、 DNA |
产生机制 | 细胞内多泡体直接与胞质膜融合以胞吐形式释放 | 细胞质膜向外以脱落或出芽形式产生 | 细胞程序性死亡或凋亡过程中形成 |
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