中国寄生虫学与寄生虫病杂志 ›› 2022, Vol. 40 ›› Issue (4): 516-523.doi: 10.12140/j.issn.1000-7423.2022.04.016

• 综述 • 上一篇    下一篇

肝多房棘球蚴病脉管侵犯的研究进展

张婷婷1,2,4(), 杜秋沛1, 郭新建3, 张灵强2,4, 王志鑫2,4, 常正松1,3, 赵乾2,4, 王海久2,4, 侯立朝2,4,*()   

  1. 1.青海大学医学院临床医学系,西宁 810001
    2.青海大学附属医院肝胆胰外科,西宁 810001
    3.青海大学附属医院病理科,西宁 810001
    4.青海省包虫病研究重点实验室,西宁 810001
  • 收稿日期:2021-09-23 修回日期:2022-01-04 出版日期:2022-08-30 发布日期:2022-09-07
  • 通讯作者: 侯立朝
  • 作者简介:张婷婷(1995-),女,硕士研究生,从事肝胆胰相关疾病研究,E-mail: 705042690@qq.com
  • 基金资助:
    青海省包虫病临床医学研究中心项目(2017-SF-L2);青海省卫生计生委一般指导性课题(2018-wjzdx-118);青海大学附属医院中青年科研基金一般项目(ASRF-2021-YB-09)

Research progress on vascular invasion of hepatic alveolar echinococcosis

ZHANG Ting-ting1,2,4(), DU Qiu-pei1, GUO Xin-jian3, ZHANG Ling-qiang2,4, WANG Zhi-xin2,4, CHANG Zheng-song1,3, ZHAO Qian2,4, WANG Hai-jiu2,4, HOU Li-zhao2,4,*()   

  1. 1. Department of Clinical Medicine, School of Medicine,Qinghai University,Xining 810001, China
    2. Department of Hepatobiliary and Pancreatic Surgery, Qinghai University Affiliated Hospital, Xining 810001, China
    3. Department of Pathology, Affiliated Hospital of Qinghai University, Xining 810001, China
    4. Qinghai Research Key Laboratory for Echinococcosis,Xining 810001, China
  • Received:2021-09-23 Revised:2022-01-04 Online:2022-08-30 Published:2022-09-07
  • Contact: HOU Li-zhao
  • Supported by:
    Project of Qinghai Echinococcosis Clinical Medical Research Centre(2017-SF-L2);General Guiding Subject of Health and Family Planning Commission of Qinghai Province(2018-wjzdx-118);General Project of Young and Middle-aged Scientific Research Fund of Affiliated Hospital of Qinghai University(ASRF-2021-YB-09)

摘要:

肝多房棘球蚴病病灶对人体重要的脉管系统(血管、胆管、淋巴结)是否侵犯及其侵犯程度,直接影响患者的手术治疗方式。目前,临床对于血管侵犯、胆管侵犯及淋巴结转移的病理状态、检查指征及治疗方式的关系尚不明确。本文综合国内外最新研究进展,对肝多房棘球蚴病的增殖与转移机制,病灶的病理分区,及脉管侵犯的肉眼、影像、显微镜下的特点进行深入阐述,以期推进肝多房棘球蚴病脉管侵犯诊断与治疗等研究的发展。

关键词: 肝多房棘球蚴病, 脉管系统, 侵犯

Abstract:

The surgical treatment for multilocular hepatic echinococcosis is determined by the severity of the lesion invasion to the important vascular system (blood vessels, bile ducts and lymph nodes). Currently, the clinical relationships among the pathological changes, examination indications and treatments of vascular invasion, bile duct invasion and lymph node metastasis are not clear. Here we have summarized recent advances worldwide in multilocular hepatic echinococcosis. The mechanisms of multilocular hepatic echinococcosis progression and metastasis, the pathological distribution of the lesions and the clinical imaging, the morphology and microscopic characteristics of the vascular invasion were reviewed. This review will shed light on the development and research of the diagnosis and treatment of vascular invasion caused by multilocular hepatic echinococcosis.

Key words: Hepatic alveolar echinococcosis, Vascular system, Invasion

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